Results 151 to 160 of about 15,769 (290)

Disciple-COA: From Agent Programming to Agent Teaching

open access: yes, 2000
This paper presents Disciple-COA, the most recent learning agent shell developed in the Disciple framework that aims at changing the way an intelligent agent is built: from “being programmed ” by a knowledge engineer, to “being taught ” by a domain ...
Dorin Marcu   +6 more
core  

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Angola, movie poster for 'The Devil's Disciple' in Luanda

open access: yes, 1961
Angola - Movie, 255The Devil's Disciple ('O Aprendiz Do Diabo') starred Burt Lancaster, Kirk Douglas, and Laurence Olivier.The Devil's Disciple (1959). IMDB.comColorVolume 106, Page
Forman, Harrison, 1904-1978
core  

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Why followership matters in psychiatry: rebalancing our obsession with leadership. [PDF]

open access: yesBJPsych Open
Laugharne RA   +7 more
europepmc   +1 more source

Disciple

open access: yesJournal of Humanistic Mathematics, 2017
openaire   +2 more sources

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