Results 131 to 140 of about 2,047,533 (295)
Engineering‐Modulated Molybdenum Enzymes Strategy for Tumor‐Specific Metabolic‐Immunotherapy
Advanced Science, EarlyView.Biodegradable molybdenum sulfide nanoparticles were synthesized via a one‐pot strategy to increase molybdenum enzyme activity and thus effectively potentiate anti‐tumor immunity by integrating molybdenum‐based metalloimmunotherapy with hydrogen sulfide gas therapy.
Xiaoxiao Pan +14 more
wiley +1 more source
Innovation Policy Report: December 2015
, 2015 The Innovation Policy Report is produced by the Department of Industry, Innovation and Science, and aims to highlight developments in the innovation policy area. It also includes references to relevant innovation documents and events.
Innovation and Science (Australia) +1 more
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A chain-interactive innovation model for the learning economy: Prelude for a proposal [PDF]
The implementation of innovation has a central role in the dynamic knowledge economy of the twenty-first century. The ability to assemble new expertise and commercialise new business propositions constitutes one of the central characteristics in today’s ...
Sandro Mendonça +2 more
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Advanced Science, EarlyView.A patient‐specific, haplotype‐resolved genome framework improves detection and interpretation of somatic variants in hepatocellular carcinoma. Using multi‐platform sequencing, the personalized assembly resolves complex regions including centromeres and MHC/HLA loci, enhances structural variant discovery, and links regulatory alterations to allele ...
Jiazheng Lin +17 more
wiley +1 more source
Communications BiologyImmunotherapy, including immune checkpoint inhibitors and adoptive cell transfer, has obtained great progress, but their efficiencies vary among patients due to the genetic and epigenetic differences.
Kanglong Yang +7 more
doaj +1 more source
Complexities in building innovation systems: the case of radical medical technologies [PDF]
, 2016 The main goal of this thesis is to facilitate a further understanding of how firms behind innovative technologies deal with different complexities in system-building strategies and the co-dependencies among different technologies, actors and system ...
Kukk, P. +2 more
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Endothelial YAP Signaling Promotes Blood‐Spinal Cord Barrier Repair in Mice After Spinal Cord Injury
Advanced Science, EarlyView.Endothelial YAP is required for blood‐spinal cord barrier repair after spinal cord injury. YAP‐dependent vascular repair is associated with ANGPT1/PI3K/AKT signaling in vivo and may involve endothelial‐pericyte paracrine interactions. By supporting vascular remodeling, tight junction restoration, restored pericyte coverage, and astrocyte‐vascular ...
Jiawei Wang +14 more
wiley +1 more source
The Notion of Creating New Knowledge in Science and Mathematics: A Conceptual Critique
Araştırma Temelli Etkinlik DergisiThis paper critically examines the contested notion of “creating new knowledge” in science and mathematics education through a conceptual literature review.
Themba M. Mthethwa, Bibin George
doaj +2 more sources
CoSP: Reconfigurable Metamaterial Inverse Design via Contrastive Pretrained Large Language Model
Advanced Science, EarlyView.In this work, CoSP (contrastive multi‐state pretrain), an intelligent inverse design method for reconfigurable metamaterials based on a contrastive pretrained large language model, is proposed. Numerical experiments demonstrate that CoSP can design reconfigurable metamaterial structures for multi‐state, multi‐band optical responses, showing great ...
Shujie Yang +4 more
wiley +1 more source
Public sector innovation toolkit
, 2016 The Public Sector Innovation Toolkit has been developed to assist individual public servants, public sector teams and agencies who want to increase the extent and effectiveness of their innovation efforts.
Innovation and Science (Australia) +1 more
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