Results 131 to 140 of about 427,190 (308)

De las obligaciones del operador disciplinario frente al principio de proporcionalidad [PDF]

open access: yes, 2014
El Operador Disciplinario es el titular de la acción disciplinaria de conformidad con las normas procedimentales en el ordenamiento jurídico interno, tales como la Ley 734 de 2002 y la Ley 836 de 2003.
Parra Ávila, Liliana Consuelo
core  

“More” Artificial mRNAs: Beyond the Art of Nature

open access: yesAdvanced Science, EarlyView.
Inspired by nature yet transcending it, synthetic mRNA is being redesigned beyond the canonical architecture. This review highlights emerging forms—circular, branched, and self‐amplifying mRNAs—that expand stability, persistence, and functional control, illustrating how artificial mRNA is evolving into a new medium for programmable biological ...
Yuanzhe Cui   +3 more
wiley   +1 more source

The Resurrection of the Duty to Inquire After Therasense v. Becton, Dickinson & Co. [PDF]

open access: yes, 2009
Balancing a duty to a tribunal and a duty to a client can paralyze a lawyer. The task raises difficult questions about how to reconcile competing obligations as an advocate and as an officer of the court.
Woolard, Brandee
core   +1 more source

Integrative Analyses Identify a cGAS‐STING Pathway‐Driven Signature With Context‐Dependent Roles in Systemic Lupus Erythematosus

open access: yesAdvanced Science, EarlyView.
Zhang et al. identify M7core, a critical cGAS‐STING pathway‐driven gene signature that is activated in most lupus patients’ blood and links to lupus disease severity, lymphopenia, and lupus nephritis. They further reveal the diagnostic and pathogenic characteristics of M7core and emphasize the importance of assessing pathway activity before initiating ...
Lele Zhang   +13 more
wiley   +1 more source

Do Disciplinary Sanctions Affect Political Parties’ Re-election? Evidence from Colombia

open access: yesJournal of Politics in Latin America
Our study examines whether citizens punish political misbehavior by estimating the impact of disciplinary sanctions on the re-election of political parties in Colombian mayoral elections. Results reveal that disciplinary sanctions have no effect on the re-election of paramilitary-linked parties.
Héctor M. Posada   +2 more
openaire   +2 more sources

Office of Anticorruption and Integrity: Annual Report 2013 [PDF]

open access: yes, 2014
[Excerpt] Corruption is not single-celled. It does not move in just one direction and has many causes and symptoms. It has no single cure and will continue to grow and fester unless addressed from multiple fronts.
Asian Development Bank
core   +1 more source

Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects

open access: yesAdvanced Science, EarlyView.
Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang   +9 more
wiley   +1 more source

When We Don\u27t See Eye to Eye: Discrepancies Between Supervisors and Subordinates in Absence Disciplinary Decisions [PDF]

open access: yes, 1992
This study provided a within-subjects assessment of the factors associated with absence disciplinary decisions for both supervisors and subordinates. In addition, this study examined discrepancies in disciplinary decisions between a supervisor and his or
Judge, Timothy A.   +1 more
core   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu   +4 more
wiley   +1 more source

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