Molecular characterization of the A52 murine hepatocellular carcinoma cell line
Hepatocellular carcinoma (HCC) is a poor outcome cancer with limited therapeutic choices. To advance therapeutic development we genetically characterized the A52 murine HCC cell line. We noted genetic changes that match a subset of human HCC and this offers the opportunity to test novel targeted therapies in syngeneic mice.
Rhys Gillman +5 more
wiley +1 more source
Modular and Precise Deuteration: The synthesis of molecules precisely deuterated at allylic, vinylic or both positions remains a challenging task. This work discloses a modular semi‐reductive deuteration that enables the synthesis of various isotopologs including precisely labeled d1‐, d2‐, d3‐, d5‐, and d7‐products.
Lihan Qi +10 more
wiley +2 more sources
Diverse Genetic Etiologies of Unilateral Polymicrogyria
Objective Polymicrogyria (PMG) is one of the most common human malformations of cortical development and is often classified by its radiographic pattern of distribution. Unilateral polymicrogyria (uPMG) is a subtype of PMG affecting a portion or all of one cerebral hemisphere.
Abbe Lai +21 more
wiley +1 more source
Medical Board Discipline of Physicians for Spreading Medical Misinformation.
Saver RS.
europepmc +1 more source
(De)Constructing invisible barriers: the gender projection model of organizational inequality. [PDF]
Gabarrot F.
europepmc +1 more source
Polyphenol‐Based Biomaterials Against Cancer Radio/Chemotherapy‐Induced Intestinal Toxicity
Radiotherapy/chemotherapy often causes intestinal toxicity, impairing cancer patients’ quality of life and treatment efficacy. Polyphenols protect against this injury via multiple mechanisms, but face oral use limitations. This review outlines their protective mechanisms and delivery challenges, highlighting recent oral delivery advances and future ...
Jixu Lu +4 more
wiley +1 more source
Student-athletes at risk: faculty voices on gender-based violence and the need for structural change in physical activity and sport sciences programs. [PDF]
Serra Payeras P +3 more
europepmc +1 more source
Legal Process Scholarship and the Regulation of Lawyers Special Issue: Institutional Choices in the Regulation of Lawyers: Foreword [PDF]
Schneyer, Ted
core +1 more source
Nanomaterial‐Mediated Near‐Infrared Photothermal Neuromodulation for Neurologic Disorders
This review summarizes how near‐infrared light activates photothermal nanomaterials to enable noninvasive neuromodulation with high spatiotemporal precision. It elucidates the underlying mechanisms, explores targeted therapeutic applications for neurological disorders, discusses integration with optogenetics and biosensors, and addresses future ...
Ting‐Ting Zeng +9 more
wiley +1 more source

