Results 101 to 110 of about 852,357 (308)

THE DISCIPLINE OF EXPRESSION [PDF]

open access: yesSchool Science and Mathematics, 1920
n ...
openaire   +2 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Ownership concentration and market discipline in European banking: Good monitoring but bad influence? [PDF]

open access: yes
We investigate the impact of banks’ ownership concentration on the effectiveness of shareholders’ market discipline. More precisely, we first assess whether the ability of the distance to default to predict banks’ financial distress is affected by the ...
Tristan AUVRAY (LEREPS-GRES)   +1 more
core  

Upaya Guru Kelas Dalam Membentuk Karakter Religius dan Disiplin Pada Siswa Kelas VI B SDS Karakter Al-Adzkiya Cianjur

open access: yesEdukasi Islami: Jurnal Pendidikan Islam
Penelitian ini bertujuan untuk menganalisis upaya yang dilakukan oleh guru kelas dalam membentuk karakter religius dan disiplin siswa kelas VI B di SDS Karakter Al-Adzkiya Cianjur.
Nur Muhammad Sofiyulloh Mujamil   +1 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

The Effects Of Fiscal And Monetary Discipline On Budgetary Outcomes [PDF]

open access: yes
This paper extends the game-theoretic model of Von Hagen and Harden (1995) that analyzes the impact of fiscal discipline on budgetary outcomes.It analyzes the effects on budgetary outcomes of both fiscal and monetary discipline, which are evaluated with ...
Bilin Neyapti
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Labor Discipline, Reputation and Underemployment Traps [PDF]

open access: yes
The introduction of "effort inducible" and non-effort" workers into an otherwise standard model of labor discipline produces a paradox of sorts: when firms cannot tell the difference, the predictable reductions in both output and real wages are sometimes
Peter Hans Matthews
core  

Home - About - Disclaimer - Privacy