Results 101 to 110 of about 630,731 (316)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The Effects Of Fiscal And Monetary Discipline On Budgetary Outcomes [PDF]

open access: yes
This paper extends the game-theoretic model of Von Hagen and Harden (1995) that analyzes the impact of fiscal discipline on budgetary outcomes.It analyzes the effects on budgetary outcomes of both fiscal and monetary discipline, which are evaluated with ...
Bilin Neyapti
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Modeling the Components of Market Discipline [PDF]

open access: yes
This paper evaluates the role of inflation-forecast heterogeneity in US monetary policy making. The deviation between private and central bank inflation forecasts is identified as a factor increasing inflation persistence and thus calling for a policy ...
Faidon Kalfaoglou, Alexandros Sarris
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Market discipline in the governance of U.S. Bank Holding Companies: monitoring vs. influencing [PDF]

open access: yes
Market discipline is an article of faith among financial economists, and the use of market discipline as a regulatory tool is gaining credibility. Effective market discipline involves two distinct components: security holders' ability to accurately ...
Robert R. Bliss, Mark J. Flannery
core  

Technology architecture: the discipline for the future definition of a manifesto

open access: yes, 2011
The author proposes a reflection on the evolution and possible future developments of Architectural Technology as an academic discipline, in light of its historical roots, through a path that sees it divided into different areas of specialized knowledge,
Gabriella Peretti, Peretti, Gabriella
core   +1 more source

Upaya Guru Kelas Dalam Membentuk Karakter Religius dan Disiplin Pada Siswa Kelas VI B SDS Karakter Al-Adzkiya Cianjur

open access: yesEdukasi Islami: Jurnal Pendidikan Islam
Penelitian ini bertujuan untuk menganalisis upaya yang dilakukan oleh guru kelas dalam membentuk karakter religius dan disiplin siswa kelas VI B di SDS Karakter Al-Adzkiya Cianjur.
Nur Muhammad Sofiyulloh Mujamil   +1 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

The effect of deposit insurance on market discipline: Evidence from a natural experiment on deposit flows [PDF]

open access: yes
We explore how the introduction of explicit deposit insurance affects deposit flows into and out of banks of varying risk levels. Using evidence from a natural experiment in Russia, we employ a difference-in-difference estimator to isolate the change in ...
Schoors, Koen   +2 more
core  

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