Results 171 to 180 of about 7,451,038 (316)

Clinical Pharmacology in China: Seven Decades of Progress in Discipline Development and Education. [PDF]

J Clin Pharmacol
Hao GX, Zhou Y, Tang BH, Zhao HJ, Wei W, van den Anker J, Zhao W.   +6 more
europepmc   +1 more source

Learning in the construction industry [PDF]

, 2006

core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Validating a novel measure of scientists' disciplinary affiliation that captures its complexity and plasticity. [PDF]

PLoS One
Pizzo GM, McCright AM, Gonnerman C, Hall TE, Plaisance KS, Robinson B.   +5 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Pediatric Eyelid Lentigo Simplex Treated With a 755-nm Picosecond Alexandrite Laser: A Case Report. [PDF]

Skin Res Technol
Tang X, Zhang C, Ye Q, Zhang T, Yan Y, Wang B.   +5 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Beggar thy neighbour or befriend thy neighbour? Asymmetric spillovers of China's double world-class policy. [PDF]

PLoS One
Hang J, Ma X.
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Sub-Acute Re-Elevated Pacing Thresholds After Atrial Leadless Pacemaker Implantation. [PDF]

J Cardiovasc Electrophysiol
Wu D, He L, Lu F, Shao Y, Li Y, Zhang E, Zhang H, Xu J.   +7 more
europepmc   +1 more source