Results 201 to 210 of about 2,361,739 (390)

Improving sexual orientation data coverage by increasing willing disclosure in recruitment [PDF]

, 2019
Leonie Nicks, Shoshana Davidson, Vivek Roy-Chowdhury, Tim Hardy   +3 more
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Panel dataset on the level of biological asset disclosure items in the financial statements of Malaysian plantation companies. [PDF]

Data Brief
Mohamed NN, Mohamed Adnan S, Sulong F, Ilias N, Khalid FM.   +4 more
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Disclosure experiences in LGBTQ+ healthcare staff: a systematic review and meta-synthesis. [PDF]

BMJ Open
Prakkash R, Manning L, Bécares L, Hatch SL, Akande I, Dorrington S.   +5 more
europepmc   +1 more source

Going-Public and the Influence of Disclosure Environment [PDF]

This paper analyzes how differences in disclosure environments affect the firms choice between private and public capital. Disclosure regulations prescribe to what extent the firm has to release confidential information that may lead to the firm ...
Marra, T.A., Suijs, J.P.M.
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

The Presence and Nature of AI-Use Disclosure Statements in Medical Education Journals: A Bibliometric Study. [PDF]

Perspect Med Educ
Ans M, Maggio LA, Algodi H, Costello JA, Driessen E, Oswald K, Lingard L.   +6 more
europepmc   +1 more source

Review of: "Qualitative Approach to Analyze Business Disclosures – A Content Analysis Perspective" [PDF]

Fredrick Kanobe
openalex   +1 more source

The effect of issuance documentation disclosure and readability on liquidity: Evidence from green bonds

, 2021
Martin Lebelle, Souad Lajili Jarjir, Syrine Sassi   +2 more
openalex   +2 more sources