Results 241 to 250 of about 420,434 (314)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Mediating effect of self-disclosure between intolerance of uncertainty and existential distress in young and middle-aged patients undergoing maintenance hemodialysis. [PDF]

Front Psychol
Pan H, Xie X, Li M.
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Planning to fail? Credibility and financing of corporate transition plans in hard-to-abate sectors. [PDF]

iScience
Klein SMA, Polzin F, Urbach X.
europepmc   +1 more source

Sexual violence disclosure in Canadian postsecondary educational institutions: a scoping review. [PDF]

BMJ Open
Jones J, Ashcroft R.
europepmc   +1 more source

Environmental disclosure and supply chain carbon leakage. [PDF]

iScience
Li M, Du W.
europepmc   +1 more source

Prognostic disclosure in metastatic breast cancer: a scoping review. [PDF]

Oncologist
Battistuzzi L, Giannubilo I, Blondeaux E, Bighin C.   +3 more
europepmc   +1 more source

Informed Consent in AI-Augmented Dentistry and Dental Research: A Scoping Review. [PDF]

Dent J (Basel)
Mihut T, Cristache CM, Oancea L, Nimigean V.   +3 more
europepmc   +1 more source