Results 301 to 310 of about 591,464 (366)

Denosumab Discontinuation

Current Osteoporosis Reports, 2022
To review the pathophysiology, the clinical consequences as well as way of mitigating the effects of denosumab discontinuation.Treatment with denosumab (DMAB) is reversible and upon discontinuation there is a rapid increase in bone turnover and a subsequent bone loss.
Anne Sophie Sølling, E. Tsourdi, T. Harsløf, B. Langdahl   +3 more
semanticscholar   +3 more sources

Hyperkalemia-Related Discontinuation of Renin-Angiotensin-Aldosterone System Inhibitors and Clinical Outcomes in CKD: A Population-Based Cohort Study.

American Journal of Kidney Diseases, 2022
RATIONALE & OBJECTIVE Renin-Angiotensin-Aldosterone system inhibitors (RAASi) are evidence-based therapies that slow the progression of Chronic Kidney Disease (CKD) but can cause hyperkalemia. We aimed to evaluate the association of discontinuing RAASi's
S. Leon, R. Whitlock, C. Rigatto, P. Komenda, C. Bohm, Ewa Sucha, S. Bota, Meltem Tuna, David Collister, M. Sood, N. Tangri   +10 more
semanticscholar   +1 more source

Discontinuation symptoms in users of selective serotonin reuptake inhibitors in clinical practice: tapering versus abrupt discontinuation

European Journal of Clinical Pharmacology, 2005
Objective: Tapering of selective serotonin reuptake inhibitor (SSRI) therapy, as opposed to abrupt discontinuation, has been recommended by several guidelines and in the literature in order to diminish the occurrence of discontinuation symptoms. However,
J G Hugtenburg, Eibert R Heerdink, A C G Egberts   +2 more
exaly   +2 more sources

Safety of Early Discontinuation of Antiseizure Medication After Acute Symptomatic Neonatal Seizures.

JAMA Neurology, 2021
Antiseizure medication (ASM) treatment duration for acute symptomatic neonatal seizures is variable. A randomized clinical trial of phenobarbital compared with placebo after resolution of acute symptomatic seizures closed early owing to low enrollment ...
John Crawford, Jeffrey Gold, Richard H. Haas   +2 more
semanticscholar   +1 more source

Discontinuation symptoms in depression and anxiety disorders

International Journal of Neuropsychopharmacology, 2007
The present overview investigates whether different antidepressants have differing discontinuation symptoms upon treatment cessation, if these symptoms vary between depression and anxiety disorders, and with length of treatment.
David S Baldwin, Stuart A Montgomery, Malcolm Lader   +2 more
exaly   +2 more sources

Discontinuation of tyrosine kinase inhibitor therapy in chronic myeloid leukaemia (EURO-SKI): a prespecified interim analysis of a prospective, multicentre, non-randomised, trial.

The Lancet Oncology, 2018
BACKGROUND Tyrosine kinase inhibitors (TKIs) have improved the survival of patients with chronic myeloid leukaemia. Many patients have deep molecular responses, a prerequisite for TKI therapy discontinuation.
S. Saussele, J. Richter, J. Guilhot, F. Gruber, H. Hjorth-Hansen, A. Almeida, J. Janssen, J. Mayer, Perttu Koskenvesa, P. Panayiotidis, U. Olsson‐Strömberg, J. Martínez-López, P. Rousselot, H. Vestergaard, H. Ehrencrona, V. Kairisto, Katerina Machova Polakova, Martin C. Müller, S. Mustjoki, M. Berger, A. Fabarius, W. Hofmann, A. Hochhaus, M. Pfirrmann, F. Mahon   +24 more
semanticscholar   +1 more source

Discontinuation and Reinitiation of Dual-Labeled GLP-1 Receptor Agonists Among US Adults With Overweight or Obesity

JAMA Network Open
Key Points Question What are the rates of and factors associated with discontinuation and subsequent reinitiation of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) among adults with overweight or obesity?
Patricia J. Rodriguez, Vincent Zhang, Samuel Gratzl, Duy Do, Brianna M. Goodwin Cartwright, Charlotte Baker, Ty J. Gluckman, N. Stucky, Ezekiel J Emanuel   +8 more
semanticscholar   +1 more source

Incidence of antidepressant discontinuation symptoms: a systematic review and meta-analysis.

Lancet psychiatry
BACKGROUND Antidepressant discontinuation symptoms are becoming an increasingly important part of clinical practice, but the incidence of antidepressant discontinuation symptoms has not been quantified.
Jonathan Henssler, Yannick Schmidt, U. Schmidt, Guido Schwarzer, Tom Bschor, Christopher Baethge   +5 more
semanticscholar   +1 more source