Results 241 to 250 of about 110,223 (318)

Health-related quality of life and lifetime QALY loss among Indigenous Australians with chronic conditions: an age-stratified analysis. [PDF]

Qual Life Res
Haque R, Luebbe A, McGrail M, Nasir BF, Alam K, Wallis K, Leedie F, Kondalsamy-Chennakesavan S.   +7 more
europepmc   +1 more source

Lessons From Drug Discovery for Cryoprotective Agent Design: An AI‐Oriented Perspective

Advanced Science, EarlyView.
Cryoprotectant design is reframed through the lens of drug discovery as a multiparameter optimization problem. This perspective highlights how AI and systematic design strategies could enable safer, more effective cryoprotectants, while identifying key limitations that currently constrain predictive progress in cryobiology. ABSTRACT Cryopreservation is
Dominika Wilczok, Jesús Valdés‐Hernández, Varinia Bernales, Alán Aspuru‐Guzik, Alex Zhavoronkov   +4 more
wiley   +1 more source

An open-source optimization model for sustainable open-pit mine production scheduling. [PDF]

Front Artif Intell
Lotsu JS, Bimpong GY, Boakye K.
europepmc   +1 more source

Large Language Model‐Informed Dual‐Track AI Framework for the Synergistic Design of Crack‐Free and High‐Strength Superalloys

Advanced Science, EarlyView.
This paper illustrates a knowledge‐augmented dual‐track AI framework for advanced superalloy design. First, Large Language Models translate metallurgical heuristics into explicit rules to rapidly prune a vast compositional search space. Subsequently, LLM‐distilled priors safely guide a reinforcement learning agent during autonomous process optimization,
Jian Yao, Junkang Wu, Jie Su, Fuzhu Wang, Zi Wang, Li Wang, Liming Tan, Lan Huang, Feng Liu, Yong Liu   +9 more
wiley   +1 more source

The effect of suturing techniques on aberrant wound recovery after total hip arthroplasty : study protocol for a prospective, randomized trial (HIP-STITCH). [PDF]

Bone Jt Open
Miedema BW, Vehmeijer SBW, van der Linden H, Hesseling B.   +3 more
europepmc   +1 more source

Learning Moisture‐Induced Damage From Vision: Diffusion Models for Real‐Time Monitoring of Additive Manufacturing Processes

Advanced Science, EarlyView.
We introduce a vision‐based real‐time monitoring system for additive manufacturing that detects subtle moisture‐induced degradation via a diffusion model‐based framework. The approach enables nondestructive assessment of moisture‐induced damage level and mechanical performance and establishes a practical route toward more intelligent, reliable, and ...
Jiyoung Jung, Yuna Yoo, Dharneedar Ravichandran, Dahyun Daniel Lim, Grace X. Gu   +4 more
wiley   +1 more source

Cost-effectiveness of inclisiran in patients with atherosclerotic cardiovascular disease from Chinese healthcare perspective. [PDF]

PLoS One
Liu M, Zhang X, Feng M, He Q, Feng Z.
europepmc   +1 more source

SPADE: A Deep Learning Framework for Spatial Mapping and Quantitative Cell–Cell Interaction Inference

Advanced Science, EarlyView.
SPADE integrates spatial transcriptomics with single‐cell RNA sequencing by using cell–cell communications (CCC) as a guide for spatial mapping. It improves cell‐type localization, enhances sparse gene‐expression signals, and reveals CCC programs at single‐spot resolution.
Xinyi Li, Ning Zhang, Zijie Jin
wiley   +1 more source

Horizontally tiled network of cortico-basal ganglia-like modules performs reinforcement learning. [PDF]

Sci Rep
Hirokane K, Takehara R, Kita T, Onoi S, Matsushita S, Kitsukawa T.   +5 more
europepmc   +1 more source