Computational simulations of tumor evolution are increasingly used to infer the rules underlying cancer growth, with the goal of one day recommending tailored treatments. Here we show that the properties of lung cancer sequencing data are best replicated by a model which assumes that cells compete both to proliferate and survive. ABSTRACT Computational
Helena Coggan +5 more
wiley +1 more source
The cost of risk score and star rating growth: insights for future Medicare advantage innovation models. [PDF]
Lissenden B, Dorneo A, Robst J, Lyu PF.
europepmc +1 more source
Rigidity‐tunable nanovesicle (P‐Pm) with mechanically induced adjuvanticity toward tumor‐associated macrophages (TAMs) was designed to engineer R848/gp100 antigen ‐loaded nanovaccine (P@Rg‐Pm), which achieved outstanding anti‐tumor outcomes in both therapeutic and preventive model of B16‐F10 melanoma.
Bangyue Luo, Liyan Qiu
wiley +1 more source
Cost-utility analysis of loxenatide versus DPP-4 inhibitors in Chinese patients with type 2 diabetes at high cardiovascular risk. [PDF]
Lai L +8 more
europepmc +1 more source
Maximizing the Energy Output of Soft Electrohydraulic Generators
Many energy resources cannot be viably harvested with electromagnetic generators. This article evaluates the potential of soft electrohydraulic generators as an alternative approach for energy capture. An analytical model charts their operational limits and a rigorous experimental study results in new performance benchmarks with maximum specific energy
Sophie Kirkman +7 more
wiley +1 more source
Cost-effectiveness of total shoulder arthroplasty: A systematic review of the evidence. [PDF]
D Gill S +5 more
europepmc +1 more source
Bistable Networks Enable Complex Shape Changes
Transition‐controlled metamaterials are networks of bistable mechanical memory that store local binary states and express them as global shape change. By decoupling low‐force programming from high‐force holding, a single lattice is reconfigured into distinct 2D profiles and 3D surfaces without continuous actuation, enabling reusable morphing materials ...
Sawyer Thomas, Jeffrey Lipton
wiley +1 more source
Cost-effectiveness analysis of finotonlimab in the treatment of advanced recurrent metastatic head and neck squamous cell carcinoma in China. [PDF]
Gao Y, Lv N, Diao R.
europepmc +1 more source
Bending‐Stable Pressure Sensor Based on Natural Wood Nanofibers for Ultra‐Low Detection Limit
A wood nanofiber‐based flexible pressure sensor with intrinsic bending‐stable performance is developed through a porous electrospun architecture and interdigital electrode design. The device exhibits an ultra‐low detection limit and stable operation under deformation for physiological monitoring and spatial sensing, providing a sustainable strategy for
Xu Zeng +7 more
wiley +1 more source
Discounting Practices in Cost-Effectiveness Analyses in Dentistry: A Systematic Review of Studies Published After 2020. [PDF]
Maruster R, Bornstein MM, Sendi P.
europepmc +1 more source

