Addressing real-world data gaps: estimating the uk population cost of crohn's disease and ulcerative colitis using a flexible cost-of-illness model informed by the optimal patient journey and IBDUK patient survey 2023. [PDF]
MacDonald R +8 more
europepmc +1 more source
Abstract Background Subthalamic nucleus deep brain stimulation (STN DBS) improves Parkinson's disease (PD)‐related motor symptoms, but how STN DBS impacts various aspects of patient‐perceived health‐related quality of life (HRQoL) is less clear. The Patient‐Reported Outcome Measurement Instrument (PROMIS) and Quality of Life in Neurological Disorders ...
Sarah A. Brinkerhoff +10 more
wiley +1 more source
Experience-dependent emergence of multi-scale spatial organization during foraging in freely moving marmosets. [PDF]
El Mahmoudi N +4 more
europepmc +1 more source
Abstract Background Friedreich ataxia (FRDA) is a rare neurodegenerative disorder with heterogenous clinical progression, complicating prognosis and trial design. Neuroimaging offers objective biomarkers of disease progression, yet variability in progression patterns remains poorly understood.
Susmita Saha +8 more
wiley +1 more source
The Economic and Clinical Impact of Recurring Automated Red Blood Cell Exchange to Manage Sickle Cell Disease in the UK. [PDF]
Medland SM +8 more
europepmc +1 more source
ChatXRD is an LLM‐driven framework that autonomously performs crystal system classification and lattice parameter prediction from XRD data. By integrating a GPT‐5‐based agent with specialized tools and decision tree reasoning, it achieves state‐of‐the‐art accuracy, enabling scalable and reliable high‐throughput materials characterization. ABSTRACT High‐
Xiaoyue He +6 more
wiley +1 more source
Health and Economic Impact and Cost-effectiveness of Produce Prescriptions for Diabetes in 50 U.S. States: A Microsimulation Study. [PDF]
Wang L +6 more
europepmc +1 more source
A knowledge‐constrained multi‐objective reinforcement learning (MORL) framework is proposed, embedding cracking susceptibility as a hard constraint to simultaneously optimize printability and mechanical properties of additively manufactured superalloys.
Pei Liu +7 more
wiley +1 more source
Decentralized Computation Offloading Strategy via Multi-Agent Deep Reinforcement Learning for Multi-Access Edge Computing Systems. [PDF]
Adu E +5 more
europepmc +1 more source
Coverage‐based rarefaction fails to quantify relative species richness
Coverage‐based rarefaction (CBR) is a high‐profile tool for assessing biodiversity that provides relative species richness estimates by leveraging the Good‐Turing index u to interpolate. In contrast to alternatives such as the Shannon and Simpson indices, CBR's main appeal is providing values in units of species. CBR is tested against a series of other
John Alroy
wiley +1 more source

