Results 181 to 190 of about 2,410,696 (333)

Collective moderation of hate, toxicity, and extremity in online discussions. [PDF]

PNAS Nexus
Lasser J, Herderich A, Garland J, Aroyehun ST, Garcia D, Galesic M.   +5 more
europepmc   +1 more source

Disintegration and discourse: Cross-sectoral story-lines in the German water and forest debates

Sabeth Häublein, Chris Seijger, Andy Selter, Tanya Baycheva-Merger, Daniela Kleinschmit   +4 more
openalex   +1 more source

STRUCTURING THE FIELD OF ZOONYMS WITH THE “PIG” ARCHISEME IN RUSSIAN DISCOURSE

, 2018
O. A. Vasilieva
openalex   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

The Representation Ahok’s Leadership Style in The Jakarta Post News: Critical Discourse Analysis

, 2018
Novia Resti Junaidi, Endry Boeriswati, Liliana Muliastuti   +2 more
openalex   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Identity drama: anti-and postcolonial discourse (based on Leslie Marmon Silko's short stories "Lullaby" and Volodymyr Danylenko's "Thunderstorms over Turovets")

, 2021
O.F. Buriak, Oksana Holnyk, Mariia Lavrusenko, Oleksandra Tsepa, Oksana Vechirko, Gareth Griffiths, Helen Tiffin, Brennan, K Brisley, Alexandra Effe, Alexander Fyfe, Annie Gagiano, C. Langlois, Jonathan Lench, Sirsha Nandi, Pramod K. Nayar, Christopher Taylor, Ryan Topper, K Brennan, Hammad Dr, Khurshid Mushtaq, Muhammad Ahmad, Rafi, A Effe, A Fyfe, A Gagiano, C Langlois, J Lench, S Nandi, P Nayar, M Pavlyshyn, C Taylor, R Topper, S Krymskyi, O Shostak   +34 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Disagreeing respectfully: embracing complexity facilitates civil discourse. [PDF]

Can Med Educ J
Lefkowitz A, Maniate JM, Kuper A.
europepmc   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source