Results 111 to 120 of about 24,602,691 (327)
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
CLIMATE CHANGE DISCOURSE. CASE STUDY: RAIFFEISEN BANK [PDF]
This study investigates the climate change discourse as this is a highly debated topic nowadays. A case study is revealed in this paper, which consists of applying the critical discourse analysis method at Raiffeisen Bank, one of the most important ...
DRAGHICI Monica +2 more
core
Language as literature: Characters in everyday spoken discourse [PDF]
, 2012 There are several linguistic phenomena that, when examined closely, give evidence that people speak through characters, much like authors of literary works do, in everyday discourse.
Sandler, Dr. Sergeiy
core
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
A Discourse Semantic Analysis of the Expository Paragraphs Written by the Eleventh Grade Students of SMAN 1 Kubu in the Academic Year 2013/2014 Based on Systemic Functional Linguistic Theory [PDF]
, 2014 This study aimed at describing and explaining the experiential meaning, interpersonal meaning and textual meaning as well as the nature of schematic structure in the students' writings under study.
Drs. I Wayan Suarnajaya,MA., Ph.D +2 more
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Molecular Oncology, EarlyView.Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley +1 more source
Mídia, cotidiano e cidade. Construções e desconstruções da observação como método
Mídia e Cotidiano, 2014 Utilizando a estética ensaística e a observação enquanto método de apropriação imediata do cotidiano, o texto pretende oferecer uma reflexão acerca das questões que envolvem o espaço, comunicação, mídia na sociedade atual.
paulo celso da silva
doaj
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source