Results 221 to 230 of about 137,620 (287)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Towards validating invalidated knowledge: a discourse analysis of firsthand accounts of hearing voices. [PDF]

BMC Psychol
Ynnesdal Haugen LS.
europepmc   +1 more source

Academic Writing Challenges in Vocational Contexts: A Discourse Analysis Approach

LATUPEIRISSA, DR. DAVID SAMUEL, BATILMURIK, DR. RIDOLOF W., SANDU, ASIHLYA   +2 more
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Participatory Surveillance and Candidacy: A Discourse Analysis of Views on Self-Testing for Proteinuria in Pregnancy. [PDF]

Qual Health Res
Jakubowski BE, Tucker KL, Lavallee L, Wilson H, Mackillop L, Chappell LC, McManus RJ, Hinton L.   +7 more
europepmc   +1 more source

B. Trigo,Foucault and Latin America: Appropriations and deployments of discoursive analysis New York:Routledge ,2004 0-415-92828-1

, 2004
F.J. Schuurman
openalex   +1 more source

THE FUNCTION OF DISCOURSE ANALYSIS IN EVALUATING THE LANGUAGE AND CONTENT OF TELEVISION HEADLINES

Kodirov, Isamitdin Kholmatjon ugli
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

The Public's Perception of Florence Nightingale's Legacy in the Digital Media: A Critical Discourse Analysis. [PDF]

Nurs Rep
Conte G, Magon A, Palmeri MA, Paglione G, Baroni I, Belloni S, Angolani M, Arcidiacono MA, Arrigoni C, Stievano A, Caruso R.   +10 more
europepmc   +1 more source

Género Y Política: Análisis Del Discurso Mediático De Hispanoamérica Y España|Gender and Politics: Media Discourse Analysis of Latin America and Spain

, 2013
Laura Teruel Rodríguez
openalex   +1 more source