Arctic Imaginaries : Poststructuralist Discourse Analysis of Chinese and Japanese Arctic Policy
, 2018 Henriika Salmi
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Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Towards validating invalidated knowledge: a discourse analysis of firsthand accounts of hearing voices. [PDF]
BMC PsycholYnnesdal Haugen LS.
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Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Participatory Surveillance and Candidacy: A Discourse Analysis of Views on Self-Testing for Proteinuria in Pregnancy. [PDF]
Qual Health ResJakubowski BE +7 more
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Reflections on the explanations of higher psychosis rates among migrant and ethnic minority populations: A critical discourse analysis. [PDF]
Transcult PsychiatryXavier SM, Iyer SN.
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Repertoires of resistance : a discourse analysis of the rhetoric of parapsychologists [PDF]
, 2016 Isaac Hughes
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An Analysis of Media Coverage, Judicial Sentencing, and Law Enforcement Perceptions of Drug Trafficking Cases in the Philippines: Implications for Fairness, Effectiveness, and Public Discourse [PDF]
Mary Gail L. Lalic - +4 more
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