Results 261 to 270 of about 23,953,214 (390)

Étude de Cas Sur le Développement de la Publication Leaders—Guide du Superviseur

open access: yesDiscourse and Writing/Rédactologie, 1986
Stewart Malcolm
doaj   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

open access: yesMolecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren   +4 more
wiley   +1 more source

News/Nouvelles

open access: yesDiscourse and Writing/Rédactologie, 1986
CJSDW Editorial Staff
doaj   +1 more source

AI Through Ethical Lenses: A Discourse Analysis of Guidelines for AI in Healthcare. [PDF]

open access: yesSci Eng Ethics
Arbelaez Ossa L   +5 more
europepmc   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

open access: yesMolecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh   +6 more
wiley   +1 more source

Functional Writing in Canada: An Overview of Career Opportunities

open access: yesDiscourse and Writing/Rédactologie, 1986
Jennifer J. Connor
doaj   +1 more source

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