Results 51 to 60 of about 22,635,034 (333)

TERRORISMO MIDIÁTICO: disseminação do medo em programa televiso francês

open access: yesMídia e Cotidiano, 2017
O estudo apresenta um programa de televisão exibido pelo canal francês France2 que revive, um ano depois, todos os detalhes dos ataques terroristas que marcaram o dia 13 novembro de 2015, em Paris, quando 130 pessoas foram mortas e outras 350 se feriram ...
Janaina Cardoso da Silva   +1 more
doaj   +1 more source

Elucidation of interface interactions between a dehydratase domain and an acyl carrier protein in cremimycin polyketide synthase

open access: yesFEBS Letters, EarlyView.
In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri   +8 more
wiley   +1 more source

Halbwachs no Hollodeck: Jogos Eletrônicos e Memória Coletiva

open access: yesMídia e Cotidiano, 2016
Este trabalho discute alguns resultados de uma pesquisa cujo objetivo era investigar se experiência lúdica dos jogos eletrônicos pode atuar como um suporte para memória coletiva e para produção e no compartilhamento de representações, de imagens e de um ...
Helyom Viana Telles
doaj   +1 more source

Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions

open access: yesFEBS Letters, EarlyView.
This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten   +10 more
wiley   +1 more source

Utopia capitulada em cifra responsável e outros temas do cinema latino-americano hoje

open access: yesMídia e Cotidiano, 2012
Devido à escalada da racionalização no que tange aos processos de produção, distribuição e exibição de filmes na América Latina entre 1990 e 2011 e pela temeridade de se pensar uma teoria do cinema sem nos reportar a uma teoria do cinema como produção ...
Sebastião Guilherme Albano da Costa   +1 more
doaj   +1 more source

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

open access: yesFEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung   +6 more
wiley   +1 more source

O Facebook como instrumento para a construção do senso comum on-line

open access: yesMídia e Cotidiano, 2013
O artigo visa expor como uma comunidade virtual pode portar-se como construtora de um senso comum (Berger e Luckmann), formando uma autoridade cultural (Zelizer) por meio das ferramentas digitais disponíveis em redes sociais (Recuero). Para tal estudo, o
Tatiana Cioni Couto
doaj   +1 more source

DiscSense: Automated Semantic Analysis of Discourse Markers [PDF]

open access: yesarXiv, 2020
Discourse markers ({\it by contrast}, {\it happily}, etc.) are words or phrases that are used to signal semantic and/or pragmatic relationships between clauses or sentences. Recent work has fruitfully explored the prediction of discourse markers between sentence pairs in order to learn accurate sentence representations, that are useful in various ...
arxiv  

Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases

open access: yesFEBS Letters, EarlyView.
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher   +6 more
wiley   +1 more source

Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones

open access: yesFEBS Letters, EarlyView.
Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley   +1 more source

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