Results 71 to 80 of about 24,207,407 (408)

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

Analyzing equivalalences in discourse: are discourse theory and membership categorization analysis comptatible [PDF]

open access: yes, 2013
Facing a crucial leap from political philosophy to empirical analysis, the approach to discourse analysis that arose in the aftermath of Laclau and Mouffe (1985), and that is currently known as the Essex school of discourse theory (DT), has in recent ...
D'hondt, Sigurd
core   +1 more source

Closing in on the picture : analyzing interactions in video recordings [PDF]

open access: yes, 2009
This paper provides a detailed account of the processing and analysing of data, obtained through video recording during reflective practitioner research.
Argyle M.   +28 more
core   +3 more sources

Políticas culturais e “Cinema Para Todos”: reflexões e caminhos possíveis

open access: yesMídia e Cotidiano, 2015
Este artigo é um desdobramento da dissertação de mestrado, defendida no PPGMC, que tem como base o projeto “Cinema para Todos” da Secretaria Estadual de Educação do Rio de Janeiro.
Patrícia Gonçalves Saldanha   +1 more
doaj   +1 more source

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

open access: yesFEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa   +8 more
wiley   +1 more source

Analysing children's accounts using discourse analysis [PDF]

open access: yes, 2005
Discourse analytic approaches to research depart from understandings of the individual and of the relation between language and knowledge provided by positivist and post-positivist approaches.
Alldred, P, Burman, E
core  

CORRA! E AS RELAÇÕES INTER-RACIAIS NA DIÁSPORA: PARA UMA DISCUSSÃO EDUCACIONAL

open access: yesMídia e Cotidiano, 2018
Este texto analisa a relação existente entre identidade do homem negro e relações inter-raciais a partir do filme Corra!. O objetivo foi verificar como a identidade do homem negro é subalternizada em um contexto de hegemonia branca.
Wellington Oliveira dos Santos
doaj   +1 more source

Documentar, ir a campo e narrar: aproximações técnicas e diálogos críticos entre Saramago e o jornalismo

open access: yesMídia e Cotidiano, 2020
Este trabalho visa expor considerações sobre os modos de produção romanesca do escritor José Saramago (1922-2010) que suscitam aproximações com o campo do jornalismo, possivelmente advindas de passagens do autor de Memorial do convento por veículos da ...
Henrique Alberto Mendes   +1 more
doaj   +1 more source

Critical Discourse Analysis and Positive Discourse Analysis – Commonalities and Differences

open access: yesMediAzioni, 2022
This study outlines an integrated new perspective on the relationship between critical discourse analysis (CDA) and positive discourse analysis (PDA). CDA typically attempts to unveil the uses of language and semiosis in the service of power and is best known for its foci on ideologically driven discrimination (gender, ethnicity, class, and related ...
openaire   +4 more sources

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

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