Results 111 to 120 of about 9,107,984 (258)
Intonation and discourse : biased questions [PDF]
, 2008 This paper surveys a range of constructions in which prosody affects discourse function and discourse structure.We discuss English tag questions, negative polar questions, and what we call “focus” questions.
Asher, Nicholas, Reese, Brian
core
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Online anti-immigrant discourse in Germany: ethnographically backed analysis of user comments
Frontiers in CommunicationThis article investigates discourse- and language-specific features of online anti-immigrant extreme speech in Germany. We analyze a context rich dataset collected and annotated through a collaborative effort involving fact-checkers, ethnographers and ...
Leah Nann, Sahana Udupa, Axel Wisiorek
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Corpora and Discourse International Conference 2020 17-19 Juni
, 2020 Diesmal digital: Vom 17.-19. Juni findet die Corpora and Discourse Conference 2020 statt. Nicht an der University of Sussex, wie vorgesehen, sondern digital.Corpora and Discourse International Conference showcases research which combine corpus ...
Marcus Mueller
core
, 2019 We report on three experiments that aim at measuring the role of prosody in the acceptability and interpretation of discourse relations between utterances connected by two French discourse markers, viz. et “and” and alors “then/well.” These two discourse
Simon, Anne-Catherine +3 more
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Recently published: Corpora and Discourse Studies
, 2015 Corpora and Discourse Studies. Integrating Discourse and Corpora The growing availability of large collections of language texts has expanded our horizons for language analysis, enabling the swift analysis of millions of words of data, aided by ...
Johanna Meyer
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source