Results 171 to 180 of about 9,107,984 (258)

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Discourse, of Course An overview of research in discourse studies

Discourse, of Course comes after Jan Renkema's Introduction to Discourse Studies (2004) for undergraduates. The new book is a collection of twenty short papers. It is a capita selecta course and meant for graduate programs.
Renkema, Jan.
core  

Exposing Deficit Discourse in Aboriginal and Torres Strait Islander Peoples' Ageing Policy: Promoting Healthy Ageing for Our Elders. [PDF]

Australas J Ageing
Howell N, Stuart L.
europepmc   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

DISCOURSE in Psychosis: introducing an international consortium for research on thought, language and communication. [PDF]

World Psychiatry
Palaniyappan L, Alonso-Sanchez MF, Bambini V, Bora E, Hinzen W, Kuperberg G, MacWhinney B, Mota N, Olah J, Rossell S, Sommer IE, Stein F, Tang SX, Voppel A.   +13 more
europepmc   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Is Narrative Enhancement Possible in Healthy Aging? A Preliminary Investigation into the Effects of Advanced Training Activities. [PDF]

J Psycholinguist Res
D'Ortenzio S, Gabbatore I, Petriglia F, Gasparotto G, Vegna G, Marini A, Bosco FM.   +6 more
europepmc   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Naturalistic language assessment and brain-network biomarkers in post-stroke aphasia for precision neurorehabilitation. [PDF]

Front Hum Neurosci
Xia J, Pei S, Zhou S, Bai Y.
europepmc   +1 more source