Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Security governance and health inequity in contemporary crises: a critical discourse analysis of securitization, exception-making, and responsibility displacement. [PDF]
Global HealthKhorram-Manesh A +3 more
europepmc +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
When silence becomes violence: a perspective on institutional discourse, digital resistance, and educational justice in Temanggung, Indonesia. [PDF]
Front SociolIrwanto I.
europepmc +1 more source
Cognitive Functions of Enumeration in Economic Discourse
Linguistic and Conceptual Views of the WorldInvestigation of linguistic means representing knowledge within the framework of cognitive linguistics pertains its relevance. Our study of enumeration is carried on the material of economic discourse. The functions of enumeration are established. Semantically enumeration constitutes of homogeneous and heterogeneous enumerative series.
openaire +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Content-function word production in Mandarin-speaking Broca's aphasia: a generative approach. [PDF]
Front NeurosciMa S, Chang H, Xi Y, Hu M.
europepmc +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Discursive structures of global development governance: a mixed-methods network analysis of an academic deliberative space in the context of FfD4. [PDF]
Front SociolDelgado-Baena J +3 more
europepmc +1 more source