Results 81 to 90 of about 45,824 (260)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The Metaphor of Struggle in Communication of the Evolutionary Theory
The objective of the paper is a Conceptual Metaphor Theory analysis of the metaphor of struggle in Darwin’s theory. The study begins with a short survey of uses of the concept of “struggle for existence” predating Darwin’s book followed by a systematic ...
Anna Drogosz
doaj
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Con el auge de los programas de educación bilingüe que utilizan el enfoque AICLE (aprendizaje integrado de contenidos y lengua extranjera), cada vez más se necesitan marcos conceptuales y prácticas para ayudar a los profesores en la integración de los contenidos, las formas de comunicación específicas para comunicar los contenidos ('literacy' en inglés)
Nashwa Nashaat-Sobhy +1 more
openaire +3 more sources
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
This study was an attempt to explore how important points are highlighted in Persian academic lectures. More specifically, this paper was aimed to reach a taxonomy of importance markers based on (a) the discourse functions of importance markers, and (b ...
Javad Zare +2 more
doaj
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
الفاعلية التواصلية وأثرها في الخطاب الديني
The purpose of the research is to show the relationship between the communicative activity and the religious discourse, as well as the basic role of the language, especially that its function is the basis of the ancients and modernists and expressive ...
معالي هاشم علي أبو المعالي +1 more
doaj +1 more source

