Results 191 to 200 of about 20,639 (306)

Linguistic Markers in At-Risk Mental States Using Natural Language Processing: A Systematic Review. [PDF]

Healthcare (Basel)
Zhang Y, Carrió A, Sevilla-Llewellyn-Jones J, Gutiérrez E, Calvo A, Navarro JB, Barajas A.   +6 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

This article explains the secrecy paradox, but don't tell anyone! [PDF]

Front Psychol
Bergman DM.
europepmc   +1 more source

DISCOURSE MARKERS IN ACADEMIC SPOKEN DISCOURSE

Philology and Culture, 2019
Marina Ivanovna Solnyshkina, Galiya Maratovna Gatiyatullina, Dina Zyavdatovna Gaynutdinova   +2 more
openaire   +1 more source

A study of vietnamese discourse markers in comparison with related french discourse markers

, 2015
This thesis puts forward a study of eleven discourse markers (DM) in vietnamese based on the framework developped by Vu Thi & Paillard (2012) taking into account the form, the scope, the discursive orientation and the semantic value. This analysis results in a distinction between three types of DM in vietnamese those introducing a point of view on the ...
openaire   +1 more source

A functional analysis of metadiscourse markers in political discourse: Persuasive strategies in Netanyahu’s speeches

This study aims to examine the persuasive impact of metadiscourse (MD) markers in political speeches. It seeks to determine the extent to which MD practices contribute to the construction of persuasive discourse within this genre.
Kazemian, Bahram, Naiyf Qaiwer, Shatha
core  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Uncertainty modeling in multimodal speech analysis across the psychosis spectrum. [PDF]

NPJ Digit Med
Rohanian M, Hüppi R, Nooralahzadeh F, Dannecker N, Pauli Y, Surbeck W, Sommer I, Hinzen W, Langer N, Krauthammer M, Homan P.   +10 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Using N400 Event-Related Potential to Detect Differences in Design-Mode and Belief-Mode Scaffold Use. [PDF]

Brain Sci
Yuan G, Begum J, Yuvaraj R, Teo CL.
europepmc   +1 more source