Results 191 to 200 of about 1,858,196 (253)

An integrative NLP framework identifies multilevel linguistic phenotypes of schizophrenia across tasks. [PDF]

Psychol Med
Nakamura H, Kano Y, Sugihara G, Takemura R, Yamaguchi Y, Shimizu M, Takagi S, Iizuka M, Tashiro S, Kitazawa M, Sento A, Takahashi H, Taishiro K.   +12 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Faithful or evasive? An empirical study on translation norm preferences of Chinese and American LLMs in Chinese official political and policy discourse. [PDF]

Front Artif Intell
Zhu X, Yin Y.
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Content-function word production in Mandarin-speaking Broca's aphasia: a generative approach. [PDF]

Front Neurosci
Ma S, Chang H, Xi Y, Hu M.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Discrete categories for continuous phenomena: discourse markers in code-switching between Italo-Romance and English/French

In this presentation, we will explore CS across three different immigration contexts, with a particular focus on discourse markers used in bilingual speech, involving some Italo-Romance heritage languages and a majority language, which can be either ...
Margherita Di Salvo, Valentina Del Vecchio   +1 more
core  

A step toward inclusion: A transparent dataset for automatic text simplification for screen reader users. [PDF]

Data Brief
Pérez-Rojas N, Solís M, Calderón-Ramírez S, Arias-Monge M, Saggion H, Xie-Li D.   +5 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Social Media Constructions of Alcohol as Emotional Coping and Social Connection in Ghana: Qualitative Study. [PDF]

JMIR Infodemiology
Thompson RG, Amuzu EK, Thompson T, Gyasi MK, Harris O, Santos GM, Ouner JJ.   +6 more
europepmc   +1 more source