Results 231 to 240 of about 204,382 (300)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Persian text readability assessment with hierarchical transformer-based classification models. [PDF]

Sci Rep
Ravanbakhsh S, Varnamkhasti MM.
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Linguistic Markers of Theory of Mind in Spontaneous Speech: A Narrative Review. [PDF]

Behav Sci (Basel)
El Mouslih C, Hodgins V, Palaniyappan L, Titone DA.   +3 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

CRISPR's cutaneous comeback: edited keratinocyte hyperplasias mimicking extramammary Paget's disease in rare vulvar squamous cell carcinoma. [PDF]

Ann Med Surg (Lond)
Saif P, Talha M, Fatima M, Hassan M, Imtiaz A.   +4 more
europepmc   +1 more source

Cognitive constraints and lexicogrammatical variability in ASD: from diagnostic discriminators to intervention strategies. [PDF]

Front Hum Neurosci
Kato S, Hanawa K.
europepmc   +1 more source

The Implicit and Explicit Prosody of the Focus Operator <i>yinwei</i> (Because) in Chinese Complex Sentences. [PDF]

Behav Sci (Basel)
Zhang L.
europepmc   +1 more source

Clinical psychopathology-based early relapse prediction model using speech and language in psychosis. [PDF]

Schizophr Res Cogn
Dalal TC, Park MTM, Silva AM, Iskhakova S, Voppel A, Brierley NJ, MacKinley M, Olarewaju E, Palaniyappan L.   +8 more
europepmc   +1 more source