Results 61 to 70 of about 20,639 (306)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The use of discourse markers in E.F.L. learners\u27 writing
, 2002 This study investigates the use of discourse markers by Spanish learners of English. It is intended as an initial contribution to the study of how discourse markers are used by foreign language learners.
Lahuerta Martínez, Ana Cristina
core
Human and automatic annotation of discourse relations for Arabic [PDF]
, 2012 This thesis describes the first, inter-disciplinary, study on human and automatic discourse annotation for explicit discourse connectives in Modern Standard Arabic (MSA).
Alsaif, Amal
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The grammatical status of discourse markers
The chapter discusses the grammatical status of discourse markers, with reference to Romance languages. The first part of the chapter is devoted to outlining some key features of discourse markers at the morphological and syntactic level.
Giacalone Ramat Anna, Fiorentini Ilaria
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The Effect of Teaching Discourse Markers through Flipped Model on Iraqi EFL Learners’ Writing Performance [PDF]
The main purpose of this study was to investigate the effect of discourse markers instruction through the flipped model on Iraqi EFL learners’ writing performance.
Ali Al Issa,Zahra Amirian,Saeed Ketabi
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
“Meh google and give”: Selected Sinhala Discourse Markers in Sri Lankan English [PDF]
OUSL JournalThis paper takes a corpus-based approach to analyzing the pragmatic functions of the Sinhala discourse markers aney, meh and ithin in Sri Lankan English (SLE) speech transcripts.
Rasudula Dissanayake, Kaushalya Perera
doaj +1 more source