Results 91 to 100 of about 1,243,760 (302)

Psychological discourses on gender, ethnicity, and socioeconomic status : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University [PDF]

open access: yes, 2001
The present study was concerned with how the discourses used in cognitive behaviour therapy (CBT), theory and practice construct the identity categories of gender, ethnicity and socioeconomic status (SES).
Patel, Asmita
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Limited Attention and Discourse Structure

open access: yes, 1996
This squib examines the role of limited attention in a theory of discourse structure and proposes a model of attentional state that relates current hierarchical theories of discourse structure to empirical evidence about human discourse processing ...
Walker, Marilyn A.
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Diskursetnologiska utmaningar

open access: yesKulturella Perspektiv, 2012
What does discourse theory “do” to ethnology? And complementarily, what does ethnology “do” to discourse theory? In this article, these two questions are approached by investigating how Swedish ethnologists have hitherto described and applied discourse ...
Jenny Gunnarsson Payne
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Discourse, hegemony, and the public sphere: A theoretical framework for the empirical modelling of memory

open access: yesMemory, Mind & Media
This article develops a model to explain the emergence and persistence of shared memory, providing a practical toolkit for empirical research in memory studies.
Anke Fiedler
doaj   +1 more source

Fantasi som diskursteoretiskt begrepp och etnologiskt blickfång

open access: yesKulturella Perspektiv, 2012
This article reviews the possibilities for utilizing the concept of fantasy in studies combining discourse theory and ethnology. It considers the Lacanian concept of fantasy that has been worked into socio-economic and cultural analysis by Jason Glynos,
Angelika Sjöstedt Landén
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

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