Results 61 to 70 of about 5,480,236 (317)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Human factors in an automotive discrete event simulation model
Acta Scientiarum: Technology, 2017 Human beings have naturally different variations in performance which may lead towards significant differences between the results forecasted by simulation models and those actually obtained.
Rafael de Carvalho Miranda +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Enhancing discrete-event simulation with big data analytics: A review
Journal of the Operational Research Society, 2019 This article presents a literature review of the use of the OR technique of discrete-event simulation (DES) in conjunction with the big data analytics (BDA) approaches of data mining, machine learning, data farming, visual analytics, and process mining ...
A. Greasley, J. S. Edwards
semanticscholar +1 more source
Automatic Parallel-Discrete Event Simulation [PDF]
, 2004 This paper describes a software enviroment devised to support parallel and sequential discrete-event simulation. It provides assistance to the user in issues such as selection of the synchronization protocol to be used in the execution of the simulation model.
openaire +4 more sources
Parallel discrete event simulation on the SpiNNaker engine
, 2013 The SpiNNaker engine is a multiprocessor system, designed with a scalable interconnection system to perform real-time neural network simulation. The scalable property of the SpiNNaker system has the potential of providing high computation power making it
Chuan Bai, Bai, Chuan
core +1 more source
Modelling Helmet Manufacturing System Using Discrete Event Simulation
Engineering ProceedingsWe simulated the manufacturing production line in a micro, small, and medium enterprise (MSME) to assess the efficiency of a helmet product organization, using ARENA simulation modelling software version 15.10.00000.
Khoong Tai Wai +5 more
doaj +1 more source
A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions
Advanced Engineering Materials, EarlyView.This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice +2 more
wiley +1 more source
Advanced Engineering Materials, EarlyView.A numerical–experimental framework is developed for characterizing multi‐matrix fiber‐reinforced polymers (MM‐FRPs) combining epoxy and polyurethane matrices. Harmonic bending tests are integrated with finite element model updating (FEMU) to simultaneously identify elastic and viscoelastic material parameters.
Rodrigo M. Dartora +4 more
wiley +1 more source