Results 61 to 70 of about 3,339,657 (284)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

ANALYSIS OF A TRANSPORT PROCESS USING HYBRID PETRI NETS [PDF]

open access: yesFiabilitate şi Durabilitate, 2013
Purpose of the paper is to analyze the Petri net model, to describe the transport process, part of amanufacturing system and its dynamics.A hibrid Petri net model is built to describe the dinamics of the transport process manufacturingsystem ...
Elisabeta Mihaela CIORTEA   +2 more
doaj  

Discrete Symmetries/Discrete Theories

open access: yes, 2012
Dynamical, metastable supersymmetry breaking appears to be a generic phenomena in supersymmetric field theories. It's simplest implementation is within the so-called "retrofitted O'Raifeartaigh Models". While seemingly flexible, model building in these theories is significantly constrained. In gauge-mediated versions, if the approximate $R$ symmetry of
Bose, Milton, Dine, Michael
openaire   +2 more sources

Compatible discrete series [PDF]

open access: yesPacific Journal of Mathematics, 2003
AmsTex file, 27 Pages; minor corrections; to appear in Pacific Journal of ...
P. Cellini   +2 more
openaire   +6 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri   +7 more
wiley   +1 more source

Dynamic Primitives in the Control of Locomotion

open access: yesFrontiers in Computational Neuroscience, 2013
Humans achieve locomotor dexterity that far exceeds the capability of modern robots, yet this is achieved despite slower actuators, imprecise sensors and vastly slower communication. We propose that this spectacular performance arises from encoding motor
Neville eHogan, Dagmar eSternad
doaj   +1 more source

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa   +10 more
wiley   +1 more source

On a discretization of confocal quadrics. II. A geometric approach to general parametrizations

open access: yes, 2017
We propose a discretization of classical confocal coordinates. It is based on a novel characterization thereof as factorizable orthogonal coordinate systems. Our geometric discretization leads to factorizable discrete nets with a novel discrete analog of
Bobenko, Alexander I.   +3 more
core   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman   +9 more
wiley   +1 more source

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