Results 41 to 50 of about 626,220 (296)

Discrete choice experiment on educating value-based healthcare [PDF]

Postgraduate Medical Journal, 2020
ABSTRACTIntroductionIdentifying costs and values in healthcare interventions as well as the ability to measure and consider costs relative to value for patients are pivotal in clinical decision-making and medical education. This study explores residents’ preferences in educating value-based healthcare (VBHC) during postgraduate medical education ...
Cindy Y G Noben, Lorette A Stammen, Sanne Vaassen, Roel Haeren, Laurents Stassen, Walther van Mook, Brigitte Essers   +6 more
openaire   +3 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Measurement and Modeling of Sustainable Food Choice and Purchasing Behavior: A Systematic Review of Methods and Models

Foods
Despite decades of methodological sophistication, research on sustainable food behavior remains critically limited in predicting actual purchases.
Tiago Negrão Andrade, Helena Maria André Bolini   +1 more
doaj   +1 more source

Willingness to Pay for Pesticides' Environmental Features and Social Desirability Bias: The Case of Apple and Pear Growers

Journal of Agricultural and Resource Economics, 2013
We conducted a discrete-choice experiment using direct and indirect valuation to determine the value apple and pear growers place on environmental features when choosing pesticides to control for first-generation codling moth.
R. Karina Gallardo, Qianqian Wang
doaj   +1 more source

Preferences of Hungarian consumers for quality, access and price attributes of health care services — result of a discrete choice experiment [PDF]

, 2012
In 2010, a household survey was carried out in Hungary among 1037 respondents to study consumer preferences and willingness to pay for health care services.
Acharya L. B., Addelman S., Austvoll-Dahlgren A., Baji P., Baji P., Becker G. S., Belicza, Berki S. E., Boncz I., Donabedian A., Donabedian A., Donabedian A., Dózsa C., Gaziano C., Gaál P., Gaál P., Hanley N., Harris K. M., Lancsar E., László Gulácsi, Milena Pavlova, Mincer J., Oldendick R. W., Pavlova M., Petra Baji, Ryan M., Ryan M., Ryan M., Telser H., Vitray J., Vroomen J. M., Wim Groot   +31 more
core   +2 more sources

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman, Asako Takanohashi, Joshua Y. Joung, Geraldine W. Liu, Kaley Arnold, Amy Pizzino, Walter Faig, Sarah Woidill, Sona Narula, Adeline L. Vanderver   +9 more
wiley   +1 more source

Using discrete choice experiments to measure preferences for hard to observe choice attributes to inform health policy decisions

Health Economics Review, 2020
Background Models of preferences in health services research (HSR) and Health Economics are often defined by readily available information, such as that captured in claims data and electronic health records.
Eline van den Broek-Altenburg, Adam Atherly   +1 more
doaj   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source