Results 31 to 40 of about 1,483,376 (248)

Intra-Pulse Modulation Recognition for Fractional Bandlimited Signals Based on a Modified MWC-Based Digital Receiver

open access: yesIEEE Access, 2020
In this paper, we present a modified modulated wideband converter (MWC)-based digital receiver for fractional bandlimited signals, and further propose an intra-pulse modulation recognition method in discrete time fractional Fourier domain (DTFrFD) for ...
Xiaomin Li, Huali Wang, Haichao Luo
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Discrete Hartley transform based multicarrier modulation

open access: yes, 2009
[[abstract]]© 2000 Institute of Electrical and Electronics Engineers - This paper presents a real-valued discrete multicarrier modulation approach that is based on the use of the discrete Hartley transform (DHT) and its inverse (IDHT) to perform the ...
Chin-Liang Wang;Ching-Hsien Chang;Fan, J.L.;Cioffi, J.M.
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Subset Optimization of Adaptive Coding and Modulation Schemes for Broadband Satellite Systems [PDF]

open access: yes, 2010
The number of Coding and Modulation Schemes suggested for the two standards DVB-S2 and DVB-RCS (in its "advanced" version) is clearly overdimensioned; a subset of schemes can be used by reducing the overall system performance negligibly.
M. Berioli   +5 more
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Modulation instability of discrete angular momentum in fiber rings [PDF]

open access: yes, 2019
We present an analysis of modulation instability in a ring of coupled optical fibers. Plane waves are shown to be unstable to perturbations carrying discrete angular momenta, both for normal and anomalous group velocity dispersion.
Biancalana, Fabio; id_orcid   +5 more
core   +1 more source

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