Results 91 to 100 of about 715,855 (195)

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

Microbial metabolite indole‐3‐propionic acid preserves astrocytic mitochondrial mitofusin 2 to limit neuroinflammation after traumatic brain injury

Interdisciplinary Medicine, EarlyView.
Following traumatic brain injury, indole‐3‐propionic acid (IPA) directly targets the aryl hydrocarbon receptor on astrocytes in the peri‐lesional cortex; this suppresses interferon regulatory factor 1‐driven transcription of the E3 ubiquitin ligase RFFL (ring finger and FYVE‐like domain containing E3 ubiquitin protein ligase).
Ziwen Zhang, Kai Wang, Liangbo Wang, Wencong Li, Hao Guo, Meng Xu, Tinghao Wang, Jiahui Ren, Ting Zhu, Jiahui Wang, Wenxing Cui, Jinpeng Zhou, Yang Tian, Liying Han, Chengxuan Guo, Shuoyao Ma, Qiang Wang, Zhihong Li, Yaning Cai, Jingyu Dong, Xun Wu, Haixiao Liu, Yan Qu   +22 more
wiley   +1 more source

With Bayesian estimation one can get all that Bayes factors offer, and more. [PDF]

Psychon Bull Rev, 2023
Tendeiro JN, Kiers HAL.
europepmc   +1 more source

Emotional Ambivalence Contextualized: The Antecedents and Consequences of Daily Affective Profiles During Pregnancy

Journal of Organizational Behavior, EarlyView.
ABSTRACT Research has increasingly highlighted the prevalence of emotionally ambivalent experiences for employees at work, with several self‐regulatory benefits emerging. Yet we do not have a full understanding of which work‐related contexts yield generative or maladaptive consequences of emotional ambivalence.
David F. Arena Jr., Jinfeng Phoenix Chen, Allison S. Gabriel, Kristen P. Jones, Devalina Nag   +4 more
wiley   +1 more source

Deep Neural Regression Prediction of Motor Imagery Skills Using EEG Functional Connectivity Indicators. [PDF]

Sensors (Basel), 2021
Caicedo-Acosta J, Castaño GA, Acosta-Medina C, Alvarez-Meza A, Castellanos-Dominguez G.   +4 more
europepmc   +1 more source

Spatial and Temporal Patterns of Extreme Hourly Rainfall in the Hawaiian Islands

International Journal of Climatology, EarlyView.
The extreme rainfall trends in Hawaiʻi were revealed by hourly rainfall data: Across islands, Kauaʻi and Hawaiʻi Island had larger events at a return period. Annual maximum series of 15 gauges showed significant positive trends. While extreme rainfall trends show increases or decreases regionally, the trends varied with rainfall duration.
Maxime Gayte, Yu‐Fen Huang, Yinphan Tsang, Pao‐Shin Chu, Thomas W. Giambelluca, Hanpei Zhang   +5 more
wiley   +1 more source

Scale of Alopecia Areata Distress (SAAD‐41): Initial Validation Part 2—Scoring, Preliminary Reference Values and Validity

JEADV Clinical Practice, EarlyView.
The SAAD‐41 is a 41‐item scale developed to comprehensively assess Alopecia Areata psychosocial patient‐reported outcomes. Results support scoring the scale at the subdomain level and provisionally at the total‐score level. The total‐score can be calculated as a sum of the 41 SAAD items, with the sum referred to as the SAAD‐41‐Total.
Kristina Gorbatenko‐Roth, Mattea Trinitapoli, Sarah Wood, Irmina Wallander, Jaime Nugent, Maria Hordinsky   +5 more
wiley   +1 more source

One-Line-of-Code Data Mollification Improves Optimization of Likelihood-based Generative Models

, 2023
Generative Models (GMs) have attracted considerable attention due to their tremendous success in various domains, such as computer vision where they are capable to generate impressive realistic-looking images.
Filippone, Maurizio, Franzese, Giulio, Michiardi, Pietro, Tran, Ba-Hien   +3 more
core  

Flow cytometric phytoplankton concentration and optical properties across instruments and laboratories

Limnology and Oceanography: Methods, EarlyView.
Abstract Flow cytometry measures the optical properties of individual cells and has become essential for enumerating and characterizing marine phytoplankton. Yet systematic comparison of measurements across instruments remains limited, hampering data comparison across laboratories and long‐term time series.
Francois Ribalet, Anne W. Thompson, E. Virginia Armbrust, Raffaella Casotti, Josep M. Gasol, Emily Peacock, Massimo C. Pernice, Nicole J. Poulton, Heidi M. Sosik, Angelicque E. White, Zackary Johnson   +10 more
wiley   +1 more source

Computing small discrete logarithms faster

, 2012
Computations of small discrete logarithms are feasible even in "secure" groups, and are used as subroutines in several cryptographic protocols in the literature.
Lange, T., Galbraith, S., Bernstein, D.J., Nandi, M.   +3 more
core   +1 more source