Designer Dynamic DNA Nanoaggregate in Living Cell for Mitochondrial Energy Restriction
This study presents the Tech‐tetrahedron, a designer dynamic DNA nanoaggregate engineered for precise mitochondrial energy restriction. Its trinity‐functionalized design integrates navigable unit, telomerase‐activated latch, and self‐assembly module.
Ruijia Deng +12 more
wiley +1 more source
Oral microbiome diversity, community- and taxon-level differences by oral human papillomavirus (HPV) and race/ethnicity. [PDF]
Byrd MC +6 more
europepmc +1 more source
The Spatiotemporal Genetic Architecture of Seed Vigor in Upland Cotton
Leveraging the semi‐automated SeedRanger platform, we profiled the germination kinetics of 356 cotton accessions at a 30‐min interval. This high‐throughput phenomic approach delineated a temporal genetic network comprising 541 stage‐specific loci. Crucially, functional validation identified FLA2 as a pivotal, auxin‐modulated regulator that orchestrates
Luyao Wang +32 more
wiley +1 more source
Bridging Pediatric to Adult Care: A Scoping Review on Transitional Care for Individuals with Congenital Heart Disease Using Data Mining Techniques to Identify Key Topics. [PDF]
Angileri S +15 more
europepmc +1 more source
Microplastics (MPs) breach the gut‐brain axis by triggering taurine‐depleting microbiota dysbiosis that accelerates Alzheimer‐like pathology in 5XFAD mice. Taurine supplementation normalizes autophagy, microglial quiescence, and cognition, and plasma taurine inversely tracks cognitive decline in ADNI participants, revealing a readily translatable ...
Zifeng Wu +8 more
wiley +1 more source
Surgical Intensity and Specialization Preferences in Healthcare: An Operation- and Process-Management Perspective Using Bibliometric Analysis, Cognitive Mapping and Analytic Network Process (ANP). [PDF]
Kılıç Y +4 more
europepmc +1 more source
Brain‐Computer Interface Training Fosters Perceptual Skills to Detect Errors
Accurate perception of visuomotor errors underpins motor precision and learning, yet conventional behavioral training fails to improve sensitivity to subtle errors. Real‐time EEG‐based brain‐computer interface feedback targeting the error positivity component enhances perceptual learning of small errors.
Deland H. Liu +4 more
wiley +1 more source
A Method Inspired by One-Dimensional Discrete-Time Quantum Walks for Influential Node Identification. [PDF]
Liang W, Wang Y, Liu Q, Zhang W.
europepmc +1 more source
An implantable phototriggered prodrug depot patch (iPDP) is presented that enables actively programmable drug release post‐implantation. Covalently conjugated prodrug ensures minimal leakage; illumination parameters serve as a code to precisely control dose per release.
Haipeng Lu +10 more
wiley +1 more source
Evolution of the NCI antibody-drug conjugate portfolio: from chemical engineering to clinical complexity. [PDF]
Zhan Q, Zeng W, Shi H, Wan H.
europepmc +1 more source

