Results 11 to 20 of about 182,355,643 (211)

Discrete Tracy--Widom operators. [PDF]

, 2009
Integrable operators arise in random matrix theory, where they describe the asymptotic eigenvalue distribution of large self-adjoint random matrices from the generalized unitary ensembles.
McCafferty, Andrew, Blower, Gordon
core   +4 more sources

Discrete exterior geometry approach to structure-preserving discretization of distributed-parameter port-Hamiltonian systems [PDF]

, 2011
This paper addresses the issue of structure-preserving discretization of open distributed-parameter systems with Hamiltonian dynamics. Employing the formalism of discrete exterior calculus, we introduce a simplicial Dirac structure as a discrete analogue
Seslija, Marko,, Scherpen, Jacquelien M.A.,, van der Schaft, Abraham, van der Schaft, Abraham; id_orcid, Arjan Van Der Schaft, Jacquelien M. A. Scherpen, van der Schaft, Arjan, Scherpen, Jacquelien M.A., Seslija, Marko, van der Schaft, Arjan ; id_orcid, Marko Seslija, Schaft, Arjan van der,   +11 more
core   +3 more sources

Generalised verification of the observer property in discrete event systems [PDF]

, 2012
The observer property is an important condition to be satisfied by abstractions of Discrete Event Systems (DES) models. This paper presents a generalised version of a previous algorithm which tests if an abstraction of a DES obtained through natural ...
Pena, Patricia N., da Cunha, A. E. C., Malik, Robi, Cury, José E. R., Bravo, H. J.   +4 more
core   +1 more source

On the Structure of Subsets of the Discrete Cube with Small Edge Boundary [PDF]

, 2018
. The edge isoperimetric inequality in the discrete cube specifies, for each pair of integers m and n, the minimum size gn(m) of the edge boundary of n an m-element subset of {0, 1} ; the extremal families (up to automorphisms of n the discrete cube) are ...
Keller, N, Lifshitz, N, ELLIS, DC
core   +3 more sources

A discrete time version for models of population dynamics in the presence of an infection [PDF]

, 2005
We present a set of difference equations which represents the discrete counterpart of a large class of continuous model concerning the dynamics of an infection in an organism or in a host population. The limiting behavior of the discrete model is studied
IZZO, GIUSEPPE, A. VECCHIO, Vecchio, Antonia   +2 more
core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Discrete port-Hamiltonian systems [PDF]

, 2005
Either from a control theoretic viewpoint or from an analysis viewpoint it is necessary to convert smooth systems to discrete systems, which can then be implemented on computers for numerical simulations.
Schaft, A.J. van der,, Clemente-Gallardo, J., Clemente Gallardo, J.J., Talasila, V., A.J. van der Schaft, Schaft, A.J. van der; id_orcid, Clemente-Gallardo, J.,, J. Clemente-Gallardo, van der Schaft, A.J., Talasila, V.,, Schaft, A.J. van der, V. Talasila   +11 more
core   +2 more sources