Results 31 to 40 of about 277,028 (248)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Finite Element Method: An Overview

open access: yesWalailak Journal of Science and Technology, 2013
The finite element method (FEM) is a numerical analysis technique for obtaining approximate solutions to a wide variety of engineering problems. A finite element model of a problem gives a piecewise approximation to the governing equations.
Vishal JAGOTA   +2 more
doaj   +1 more source

Effect of envelope characteristics on the accuracy of discretized greenhouse model in TRNSYS

open access: yesJournal of Agricultural Engineering, 2022
TRNSYS is a common tool that has been recently used to model and simulate greenhouse energy demand and utilization using building energy simulation (BES).
Qazeem Opeyemi Ogunlowo   +6 more
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Discrete Takagi-Sugeno Fuzzy Models Applied to Control the Knee Joint Movement of Paraplegic Patients

open access: yesIEEE Access, 2020
In this manuscript, a method for designing Takagi-Sugeno (T-S) fuzzy discrete-time regulators based on linear matrix inequalities (LMIs) is proposed to control the variation of the knee joint angle movement of paraplegic patients through electrical ...
Ruberlei Gaino   +6 more
doaj   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

MORPHOLOGICAL SAMPLING OF CLOSED SETS

open access: yesImage Analysis and Stereology, 2011
We briefiy survey the standard morphological approach (Heijmans, 1994) to the sampling (or discretization) of sets. Then we summarize the main results of our metric theory of sampling (Ronse and Tajine, 2000; 2001; 2002; Tajine and Ronse, 2002), which ...
Christian Ronse, Mohamed Tajine
doaj   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin   +12 more
wiley   +1 more source

THE DISCRETIZATION OF THE POLARIZED SIGNAL

open access: yesНаучный вестник МГТУ ГА, 2018
Often, the monitoring systems solution of remote sensing problems, recognition (classification, discrimination) of radar objects using radio polarimetry methods is required in real time mode with the display of the current information on the radar ...
P. E. Korneev
doaj   +1 more source

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