Results 151 to 160 of about 584,742 (263)

Using Discriminant Analysis to Predict Frailty in Community-Dwelling Older Adults in Taiwan. [PDF]

open access: yesJ Nurs Res
Yang MH   +6 more
europepmc   +1 more source

A Metabolomic Signature Predicts Gout Flare Clinical Outcome Associated With Colchicine Prophylaxis

open access: yesArthritis &Rheumatology, EarlyView.
Objective This study investigated that serum metabolomics, before urate‐lowering therapy (ULT) initiation, could serve as a biomarker for responsiveness to colchicine prophylaxis in patients with gout commencing treat‐to‐target ULT. Methods We studied a multicenter prospective cohort (n = 409) initiating treat‐to‐target ULT plus colchicine prophylaxis.
Wenyan Sun   +13 more
wiley   +1 more source

Unveiling Endotypes in Systemic Lupus Erythematosus Through Multi‐Omic Analysis: Insights into Cardiovascular and Renal Complications

open access: yesArthritis &Rheumatology, Accepted Article.
Background Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.
Tomás Cerdó   +84 more
wiley   +1 more source

Discriminating models of trait evolution. [PDF]

open access: yesEvolution
Roa Lozano J   +4 more
europepmc   +1 more source

Effective performance of the 2022 American College of Rheumatology/European Alliance of Associations for Rheumatology classification criteria for Antineutrophil‐Cytoplasmic‐Antibody‐Associated Vasculitis in Pediatric Patients: an ARChiVe Study

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To assess the 2022‐ACR/EULAR classification criteria for ANCA‐associated vasculitis (AAV) in children with chronic small‐to‐medium vessel vasculitis. Methods A cohort of 574 patients, identified by physician's‐(MD)‐diagnosis in A‐Registry‐of‐Childhood‐Vasculitis, were classified by computation of registry data, as having granulomatosis with ...
David A. Cabral   +41 more
wiley   +1 more source

Autoantibodies to Joint‐Related Peptides Are Associated with Onset of Rheumatoid Arthritis in Presymptomatic Seronegative Individuals

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To identify autoantibodies in presymptomatic individuals that associate with the onset of rheumatoid arthritis (RA), and to distinguish early RA from osteoarthritis (OA), particularly in individuals lacking classic RA serological markers. Methods We analyzed serum and plasma from three cohorts: pre‐symptomatic individuals who later developed ...
Outi Sareila   +12 more
wiley   +1 more source

Layer-Specific Astrocyte Morphological Responses in the CA3 Hippocampus Region During Piry Virus-Induced Encephalitis. [PDF]

open access: yesHippocampus
de Almeida Miranda D   +10 more
europepmc   +1 more source

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

open access: yesBMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng   +10 more
wiley   +1 more source

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