Results 71 to 80 of about 169,803 (261)

Machine Learning‐Enhanced Ultrasensitive Immuno‐CRISPR Array Facilitates Early Diagnosis of Alzheimer's Disease by Detecting Multiple Plasma Biomarkers

Advanced Science, EarlyView.
This work presents a CRISPR‐based, ultrasensitive multiplex protein detection array capable of simultaneously analyzing six plasma biomarkers associated with Alzheimer's disease (AD). By integrating antibody‐mediated signal transduction, recombinase polymerase amplification, and spatially encoded CRISPR‐Cas12a, the system achieves detection sensitivity
Liding Zhang, Changwen Yang, Qian Yao, Xuewei Du, Shuai Ding, Yaoqiang Shi, Can Sheng, Ming Wang, Ying Han, Haiming Luo   +9 more
wiley   +1 more source

netQDA: Local Network-Guided High-Dimensional Quadratic Discriminant Analysis

Mathematics
Quadratic Discriminant Analysis (QDA) is a well-known and flexible classification method that considers differences between groups based on both mean and covariance structures. However, the connection structures of high-dimensional predictors are usually
Xueping Zhou, Wei Chen, Yanming Li
doaj   +1 more source

Use of discriminant analysis to identify propensity for purchasing properties

GEPROS: Gestão da Produção, Operações e Sistemas, 2015
Properties usually represent a milestone for people and families due to the high added-value when compared with family income. The objective of this study is the proposition of a discrimination model, by a discriminant analysis of people with ...
Ricardo Floriani, Silvana Silva Vieira Tambosi, Nelson Hein   +2 more
doaj   +1 more source

Microplastics‐Induced Gut Microbiota Dysbiosis Accelerates Alzheimer's‐Like Pathology and Cognitive Decline via the Gut–Brain Axis

Advanced Science, EarlyView.
Microplastics (MPs) breach the gut‐brain axis by triggering taurine‐depleting microbiota dysbiosis that accelerates Alzheimer‐like pathology in 5XFAD mice. Taurine supplementation normalizes autophagy, microglial quiescence, and cognition, and plasma taurine inversely tracks cognitive decline in ADNI participants, revealing a readily translatable ...
Zifeng Wu, Jiarong Yang, Miaoxuan Zhang, Yi Li, Zhuling Tu, Ji Wang, Jin‐Tai Yu, Kun Guo, Rongcan Luo   +8 more
wiley   +1 more source

Multilinear Laplacian discriminant analysis for gait recognition

IET Computer Vision, 2017
The extraction of discriminative features in presence of covariates for robust human gait recognition is a challenging task. The effect of covariate can be modelled as unknown feature contamination problem resulting in the conversion of useful or ...
Risil Chhatrala, Dattatray V. Jadhav
doaj   +1 more source

Classification of selected Slovak variety wines.

Kvasný průmysl, 2000
During a three years period, the content of the selected volatile substances has been detected in the Slovak varietal wines, Welschriesling, Grüner Veltliner and Müller Thurgau. The acquired data were achieved by means of different multivariation methods
J. PEŤKA, B. BALLA, P. FARKAŠ, J. MOCÁK, M. KOVÁČ   +4 more
doaj   +1 more source

Identification of a Nonribosomal Peptide Analog With Activity Against Multiple Gram‐Positive Bacteria via a Synthetic Bioinformatic Natural Product Discovery Approach

Advanced Science, EarlyView.
The genome of Rhodococcus erythropolis D‐1 was analyzed by bioinformatic tools to mine a novel nonribosomal peptide synthetase (NRPS) gene cluster. A nonribosomal peptide analog ZURJC5 associated with the NRPS was chemically synthesized. Through structure‐activity relationship studies, ZURJC28 was ultimately obtained and showed antibacterial activity ...
Keyi Chen, Jiayi Liang, Yujia Wu, Jianan Xu, Yi Liu, Wenguang Wang, Xinhang Jiang, Benjie Gao, Yueyue Wang, Hui Jiang   +9 more
wiley   +1 more source

KARAKTERISTIK ENTREPRENEUR MELALUI MULTIPLE DISKRIMINAN ANALISIS (Studi Pada Etnis Tionghoa, Jawa dan Minang di Bekasi Utara)

Jurnal Riset Manajemen Sains Indonesia, 2015
The purpose of this study is : 1) To find a description about demographic of Chinese ethnic, Javanese ethnic and Minang ethnic. 2) To discriminant test between Chinese ethnic and Javanese ethnic.
Agung Wahyu Handaru, Magdalena Prita Pagita, Widya Parimita   +2 more
doaj   +1 more source

Multi‐Component Functionalized Bifidobacterium Longum Hydrogel for Multi‐Target Integrated Therapy of Colitis‐Associated Anxiety and Depression

Advanced Science, EarlyView.
A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang, Yujie Zhang, Jiansheng He, Shunlian Li, Qingyan Ma, Qiao Li, Yudan Zhang, Yiyang Wang, Shaobo Ma, Songyan Jin, Chune Li, Xueyong Xie, Hang Zhang, Junze Deng, Xueqin Song, Daocheng Wu, Xiancang Ma, Feng Zhu   +17 more
wiley   +1 more source

Evaluatıon Of Dentofacıal Morphology In Class Iıı Malocclusıon

Turkish Journal of Orthodontics, 1996
In order to evaluate dentofacial morphology and to classify the individuals according to their features, the children with Class III malocclusion was compared to Class I normal occlusion. 189 lateral cephalometric radiographs.
Sema Yüksel
doaj   +1 more source