Results 91 to 100 of about 1,160,952 (340)
Societies, 2019 Since the 1980s, the fear of child sexual abuse (CSA) has become a major cultural feature of a large part of the Western world. Internationally, the unintended consequences of the fear surrounding CSA are rarely investigated and doing so is often ...
Else-Marie Buch Leander +2 more
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Statistical discrimination [PDF]
The Philosophers' Magazine, 2016 Racial discrimination uses race as grounds to discriminate in the treatment owed to others; sexual discrimination uses people's sexual features as grounds for determining how they should be treated compared to others. Analogously, statistical discrimination treats statistical inferences about the groups to which individuals belong as grounds for ...
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FEBS Open Bio, EarlyView.TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo +11 more
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Molecules, 2017 Discrimination between enantiomers is an important subject in medicinal and biological chemistry because they exhibit markedly different bioactivity and toxicity.
Hironori Tsuchiya, Maki Mizogami
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Discriminating among the discriminator bases of tRNAs
Chemistry & Biology, 1997 Aminoacyl-tRNA synthetases must select their specific tRNAs from the 20 structurally similar tRNAs present in a cell. The discriminator base, at position 73 of the tRNA, is important for this selection but its effects on aminoacylation are variable depending on context. Recent structural studies provide insight into this variability.
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FEBS Open Bio, EarlyView.Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr +5 more
wiley +1 more source
French Translation and Validation of Three Scales Evaluating Stigma in Mental Health
Frontiers in Psychiatry, 2017 ObjectiveThe concept of stigma refers to problems of knowledge (ignorance), attitudes (prejudice), and behavior (discrimination). Stigma may hinder access to care, housing, and work. In the context of implementation of programs such as “housing first” or
Carla Garcia +4 more
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High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer
FEBS Open Bio, EarlyView.Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson +5 more
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Detecting rs‐fMRI Networks in Disorders of Consciousness: Improving Clinical Interpretability
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Preserved resting‐state functional MRI (rs‐fMRI) networks are typically observed in Disorders of Consciousness (DOC). Despite the widespread use of rs‐fMRI in DOC, a systematic assessment of networks is needed to improve the interpretability of data in clinical practice.
Jean Paul Medina Carrion +15 more
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Railway Discriminations and Industrial Combinations [PDF]
, 1900 Charles A. Prouty
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