Results 101 to 110 of about 1,158,568 (364)

Enhancing patient engagement in cancer research: a focus on patient‐centric approaches to scientific discovery

open access: yesMolecular Oncology, EarlyView.
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda   +3 more
wiley   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Guidelines for Preventing Child Sexual Abuse and Wrongful Allegations against Staff at Danish Childcare Facilities

open access: yesSocieties, 2019
Since the 1980s, the fear of child sexual abuse (CSA) has become a major cultural feature of a large part of the Western world. Internationally, the unintended consequences of the fear surrounding CSA are rarely investigated and doing so is often ...
Else-Marie Buch Leander   +2 more
doaj   +1 more source

On the prevalence of racial discrimination in the United States

open access: yesPLoS ONE, 2019
Boutwell, Nedelec, Winegard, Shackelford, Beaver, Vaughn, Barnes, & Wright (2017) published an article in this journal that interprets data from the Add Health dataset as showing that only one-quarter of individuals in the United States experience ...
Randy T. Lee   +3 more
semanticscholar   +1 more source

Discriminating among the discriminator bases of tRNAs

open access: yesChemistry & Biology, 1997
Aminoacyl-tRNA synthetases must select their specific tRNAs from the 20 structurally similar tRNAs present in a cell. The discriminator base, at position 73 of the tRNA, is important for this selection but its effects on aminoacylation are variable depending on context. Recent structural studies provide insight into this variability.
openaire   +3 more sources

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Discrimination of Stereoisomers by Their Enantioselective Interactions with Chiral Cholesterol-Containing Membranes

open access: yesMolecules, 2017
Discrimination between enantiomers is an important subject in medicinal and biological chemistry because they exhibit markedly different bioactivity and toxicity.
Hironori Tsuchiya, Maki Mizogami
doaj   +1 more source

Ancilla-Assisted Discrimination of Quantum Gates [PDF]

open access: yesarXiv, 2008
The intrinsic idea of superdense coding is to find as many gates as possible such that they can be perfectly discriminated. In this paper, we consider a new scheme of discrimination of quantum gates, called ancilla-assisted discrimination, in which a set of quantum gates on a $d-$dimensional system are perfectly discriminated with assistance from an $r-
arxiv  

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

French Translation and Validation of Three Scales Evaluating Stigma in Mental Health

open access: yesFrontiers in Psychiatry, 2017
ObjectiveThe concept of stigma refers to problems of knowledge (ignorance), attitudes (prejudice), and behavior (discrimination). Stigma may hinder access to care, housing, and work. In the context of implementation of programs such as “housing first” or
Carla Garcia   +4 more
doaj   +1 more source

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