Results 71 to 80 of about 2,646,418 (340)
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Stereotypier, diskriminering og slåssing
Arbeiderhistorie, 2019 Italienerne var blant de første innvandrerne til Norge på 1950-tallet. Årsakene til at italienerne flyttet til denne avsidesliggende delen av Europa skilte seg ut fra de som drev den italienske migrasjonen rettet mot andre europeiske land i samme periode.
Monica Miscali
doaj +1 more source
Statistical discrimination [PDF]
The Philosophers' Magazine, 2016 Racial discrimination uses race as grounds to discriminate in the treatment owed to others; sexual discrimination uses people's sexual features as grounds for determining how they should be treated compared to others. Analogously, statistical discrimination treats statistical inferences about the groups to which individuals belong as grounds for ...
openaire +2 more sources
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
PUTTING RACIAL EQUALITY ONTO THE GLOBAL HUMAN RIGHTS AGENDA
Sur: International Journal on Human Rights, 2018 Equality is generally marginalized within the global human rights agenda, and among those who wield power in the formation and execution of this agenda.
E. Tendayi Achiume
doaj
When Does Sexuality-Based Discrimination Motivate Political Participation?
, 2017 The established consensus in political behavior research is that discrimination by political institutions motivates marginalized groups to vote and protest their conditions.
Page, Douglas D.
core +1 more source
Dispositional Hardiness and Women’s Well-Being Relating to Gender Discrimination: The Role of Minimization [PDF]
, 2003 Three studies examined whether personality-based hardiness would be associated with mental health benefits in contexts of gender discrimination. Hardy women encountering both a laboratory simulation and a hypothetical scenario of discrimination showed ...
Dion, Kenneth L., Foster, Mindi D
core +2 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Auditory Discrimination and Auditory Sensory Behaviours in Autism Spectrum Disorders [PDF]
, 2009 It has been hypothesised that auditory processing may be enhanced in autism spectrum disorders (ASD). We tested auditory discrimination ability in 72 adolescents with ASD (39 childhood autism; 33 other ASD) and 57 IQ and age-matched controls, assessing ...
Charman, Tony, Jones, Catherine
core +1 more source