Results 81 to 90 of about 1,160,952 (340)

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

open access: yesMolecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova   +26 more
wiley   +1 more source

THE LEGAL ASPECTS OF THE MOBBING IN THE REPUBLIC OF MACEDONIA [PDF]

open access: yesJournal of Process Management and New Technologies, 2014
Workplace mobbing as a form of psychological terrorism in the Republic of Macedonia is relatively new phenomenon which in the last decade is causing huge attention in the legal theory and practice.
Andon Majhosev   +3 more
doaj  

DISKRIMINASI NEGARA TERHADAP AGAMA DI INDONESIA, STUDI ATAS PERSOALAN POSISI HUKUM TOWANI TOLOTANG PASCA PENGAKUAN AGAMA RESMI

open access: yesJurnal Kawistara, 2011
This paper aims to analyze the legal position of Towani Tolotang in the case of restrictions on religion in Indonesia. This paper is based on research toward the Towani Tolotang community in the Sidenreng Rappang Regency.
Hasse J. Hasse J.
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Implicit Discrimination

open access: yes, 2018
Implicit Discrimination Author(s): Marianne Bertrand, Dolly Chugh and Sendhil Mullainathan Source: The American Economic Review, Vol. 95, No. 2, Papers and Proceedings of the One Hundred Seventeenth Annual Meeting of the American Economic Association ...

semanticscholar   +1 more source

Discrimination in the United States: Experiences of lesbian, gay, bisexual, transgender, and queer Americans

open access: yesHealth Services Research, 2019
Objective To examine reported experiences of discrimination against lesbian, gay, bisexual, transgender, and queer (LGBTQ) adults in the United States, which broadly contribute to poor health outcomes.
L. S. Casey   +6 more
semanticscholar   +1 more source

Biophysical characterization and ion transport with cell‐based and proteoliposome reconstitution assays of invertebrate K+‐Cl− cotransporters

open access: yesFEBS Open Bio, EarlyView.
The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo   +4 more
wiley   +1 more source

Errors in Discrimination [PDF]

open access: yesThe Annals of Mathematical Statistics, 1961
The probabilities of misclassification involved in the use of estimated discriminant functions are subject to chance variations. The author's purpose in this paper is to derive the distribution laws that the probabilities of misclassification follow and to obtain their expected values. The parent populations are assumed to be normal.
openaire   +3 more sources

Combining Simple Discriminators for Object Discrimination [PDF]

open access: yes, 2002
We propose to combine simple discriminators for object discrimination under the maximum entropy framework or equivalently under the maximum likelihood framework for the exponential family. The duality between the maximum entropy framework and maximum likelihood framework allows us to relate two selection criteria for the discriminators that were ...
S. Mahamud   +2 more
openaire   +2 more sources

Interaction of class III cellobiose dehydrogenase with lytic polysaccharide monooxygenase

open access: yesFEBS Open Bio, EarlyView.
The activity of lytic polysaccharide monooxygenase (LPMO) is supported by its auxiliary enzyme cellobiose dehydrogenase (CDH). The catalytic activity of both enzymes is coupled by electron transfer and a cyclic cascade generating substrates for both enzymes – hydrogen peroxide for LPMO and oxidized and non‐oxidized cellobiose and cello‐oligosaccharide ...
Angela Giorgianni   +4 more
wiley   +1 more source

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