Results 121 to 130 of about 941,916 (317)

PRELIVE: A Framework for Predicting Lipid Nanoparticles In Vivo Efficacy and Reducing Reliance on Animal Testing

open access: yesAdvanced Functional Materials, EarlyView.
PREdicting LNP In Vivo Efficacy (PRELIVE) framework enables the prediction of lipid nanoparticle (LNPs) organ‐specific delivery through dual modeling approaches. Composition‐based models using formulation parameters and protein corona‐based models using biological fingerprints both achieve high predictive accuracy across multiple organs.
Belal I. Hanafy   +3 more
wiley   +1 more source

Pixelation‐Free, Monolithic Iontronic Pressure Sensors Enabling Large‐Area Simultaneous Pressure and Position Recognition via Machine Learning

open access: yesAdvanced Functional Materials, EarlyView.
A pixelation‐free, monolithic iontronic pressure sensor enables simultaneous pressure and position sensing over large areas. AC‐driven ion release generates spatially varying impedance pathways depending on the pressure. Machine learning algorithms effectively decouple overlapping pressure–position signals from the multichannel outputs, achieving high ...
Juhui Kim   +10 more
wiley   +1 more source

From Bug to Feature: Harnessing Cross‐Sensitivity for Multiparametric Luminescence Sensing

open access: yesAdvanced Functional Materials, EarlyView.
Cross‐sensitivity in luminescence sensing is reframed from a limitation into a resource for multiparametric detection. Using ruby microspheres as a model system, cross‐sensitivity is quantitatively assessed and exploited through linear discriminant analysis, enabling simultaneous, correction‐free pressure and temperature sensing with a single ...
Nikita Panov   +5 more
wiley   +1 more source

Amyloidogenic Peptide Fragments Designed From Bacterial Collagen‐like Proteins Form Hydrogel

open access: yesAdvanced Functional Materials, EarlyView.
This study identified amyloidogenic sequence motifs in bacterial collagen‐like proteins and exploited these to design peptides that self‐assemble into β‐sheet fibers and form hydrogels. One hydrogel supported healthy fibroblast growth, showing promise for biocompatible materials. Our work demonstrates that bacterial sequences can be harnessed to create
Vamika Sagar   +5 more
wiley   +1 more source

The Impact of Perceived Discrimination on Mobile Phone Addiction Among Chinese Higher Vocational College Students: A Chain Mediating Role of Negative Emotions and Learning Burnout

open access: yesPsychology Research and Behavior Management
Wenping Li,1 Ting Xu,2 Liuting Diao,2 Qishu Wu3 1Prudence College, Zhejiang Business Technology Institute, Ningbo, People’s Republic of China; 2Business School, Ningbo University, Ningbo, People’s Republic of China; 3Zhejiang Business Technology ...
Li W, Xu T, Diao L, Wu Q
doaj  

The Neuronal Hypofunction of Subdivisions of the Prefrontal Cortex Shows Differential Effects on Contingency Judgment Learning to Gauge Fear Responses

open access: yesNeuroscience Insights
Previous studies have indicated that the infralimbic (IL) and prelimbic (PL) subdivisions of the medial prefrontal cortex (mPFC) serve as critical modulators of fear suppression and expression.
Tyler W Bailey   +3 more
doaj   +1 more source

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