Results 181 to 190 of about 941,916 (317)

Prenatal protein malnutrition impairs visual discrimination learning in adult rats [PDF]

, 1991
John Tonkiss, Janina R. Galler, Barbara Shukitt‐Hale, Frederick J. Rocco   +3 more
openalex   +1 more source

Nurr1 Orchestrates Claustrum Development and Functionality

Advanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan, Andrew G. Newman, Pauline Lange, Susanne Müller, Marco Foddis, Stefan Paul Koch, Philipp Böhm‐Sturm, Maron Mantwill, Carsten Finke, Penghui Deng, Melissa Long, Dietmar Schmitz, Victor Tarabykin   +12 more
wiley   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Improved visual discrimination learning in mice with partial 5-HT2B gene deletion. [PDF]

Neurosci Lett, 2020
Radke AK, Piantadosi PT, Uhl GR, Hall FS, Holmes A.   +4 more
europepmc   +1 more source

Incentive effects and social class in children’s probability and discrimination learning [PDF]

, 1967
Gary M. Olson, Daniel J. Bibelheimer, Harold W. Stevenson   +2 more
openalex   +1 more source

Immune Predictors of Radiotherapy Outcomes in Cervical Cancer

Advanced Science, EarlyView.
This study reveals dynamic immune remodeling in cervical cancer following radiotherapy. Single‐cell analysis identifies the C3/C3AR1 axis as a central mediator of epithelial–myeloid crosstalk, whose inhibition reduces treatment efficacy in mice. Guided by these insights, the eight‐feature machine‐learning model: Cervical Cancer Radiotherapy Immune ...
Linghao Wang, Jie Zhu, Zequn Ding, Zhiyuan Xie, Xingchen Liu, Feihong Zhang, Xiaojun Liu, Yan Zhang, Haiyan Chen   +8 more
wiley   +1 more source

Choice Outweighs Effort: Facilitating Complementary Knowledge Fusion in Federated Learning via Re-Calibration and Merit-Discrimination

Ming Yang, Dongrun Li, Xin Wang, Xiaoyang Yu, Xiaoming Wu, Shibo He   +5 more
openalex   +1 more source

Artificial Tactile Perception System for Exploring Internal and External Features of Objects via Time‐Frequency Features

Advanced Science, EarlyView.
By engaging in different active exploration behaviors, the tactile perception system can generate distinct signal modes, enabling the application of targeted decoding strategies for efficient and accurate perception of both external and internal object features.
Yuanzhi Zhou, Jingqi Zhang, Linyi Li, Muxing Huang, Ziyi Zhang, Xingmin Lu, Zilan Li, Xuchun Gui, Xinming Li   +8 more
wiley   +1 more source

Sex-dependent differences in the ability of nicotine to modulate discrimination learning and cognitive flexibility in mice. [PDF]

J Neurochem
Aomine Y, Shimo Y, Sakurai K, Abe M, Macpherson T, Macpherson T, Ozawa T, Hikida T.   +7 more
europepmc   +1 more source

Behavioral and Neural Bases of Tactile Shape Discrimination Learning in Head-Fixed Mice. [PDF]

Neuron, 2020
Kim J, Erskine A, Cheung JA, Hires SA.
europepmc   +1 more source