Results 101 to 110 of about 40,865 (297)

Interpretable machine learning approach for electron antineutrino selection in a large liquid scintillator detector

open access: yesPhysics Letters B
Several neutrino detectors, KamLAND, Daya Bay, Double Chooz, RENO, and the forthcoming large-scale JUNO, rely on liquid scintillator to detect reactor antineutrino interactions.
A. Gavrikov   +67 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Deligne Pairings and Discriminants of Algebraic Varieties

open access: yes, 2013
Let V be a finite dimensional complex vector space and V^* its dual and let X in P(V) be a smooth projective variety of dimension n and degree d at least two. For a generic n-tuple of hyperplanes H_1,...,H_n in P(V^*)^n, the intersection of X with H_1,...,H_n consists of d distinct points.
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Properness defects of projection and minimal discriminant variety

open access: yesJournal of Symbolic Computation, 2011
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

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