Results 41 to 50 of about 19,607,477 (309)

Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano   +7 more
wiley   +1 more source

Cognitive Functioning in Vorinostat‐Treated Pediatric and Young Adult Patients Over the First 180 Days After Hematopoietic Stem Cell Transplant

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Cognitive and psychological difficulties could negatively interfere with treatment adherence and quality of life before and after hematopoietic stem cell transplant (HSCT). Methods to mitigate these changes may have positive effects on treatment success.
Kristen L. Votruba   +11 more
wiley   +1 more source

Some Thoughts on the Role of the Critical Intellectual in Contemporary Germany

open access: yesPORTAL: Journal of Multidisciplinary International Studies, 2005
The paper starts by relating the notion of the "critical intellectual" to the notion of "agent of social change" on the one hand, and to other potential types of agents of change on the other: women in revolt, artists, exiles and queer agencies ...
Erich Steiner
doaj   +1 more source

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm   +10 more
wiley   +1 more source

Historiography of science and technology in focus. A discussion with Professor Robert Fox

open access: yesStudia Historiae Scientiarum, 2017
The article is an extended discussion with a laureate of numerous international distinctions, Professor Robert Fox, about his career, intellectual fascinations, as well as changing methods, styles, approaches and themes in the historiography of science ...
Robert Fox, Michał Kokowski
doaj   +1 more source

PENGEMBANGAN SISTEM INFORMASI KEMAJUAN AKADEMIK MENGGUNAKAN MODEL INCREMENTAL BERBASIS EVALUASI USABILITY DAN WHITE BOX TESTING

open access: yesSINTECH (Science and Information Technology) Journal, 2021
This research aims to develop an Academic Progress Information System (SIsKA) in the Computer Science Study Program, Postgraduate Program at Ganesha University of Education. The incremental development model is used in the development of SIsKA.
I Made Agus Oka Gunawan   +2 more
doaj   +1 more source

Evaluation of the Utility of Baseline Echocardiogram in Patients With Standard Risk Precursor B‐Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
Abstract Background A routine baseline echocardiogram is often obtained prior to anthracycline administration in children with cancer. The utility of baseline echocardiogram is unclear in patients with standard risk B‐cell acute lymphoblastic leukemia (SR B‐ALL) as their anthracycline cumulative dose is low.
Ziyad Alrajhi   +4 more
wiley   +1 more source

A Critical Analysis of Characteristics that Influence the Effect of Instructor Discussion Interaction on Student Outcomes

open access: yesOnline Learning, 2017
Teacher presence facilitates students’ social and cognitive presence in online courses. Instructor interaction in discussion forums, a widely adopted instructional strategy, establishes teacher presence but research on the optimal frequency and content ...
Rebecca Simon Hoey
doaj   +1 more source

Gemcitabine, Docetaxel, Melphalan, Carboplatin as Part of Sequential Cycles of High‐Dose Chemotherapy With Autologous Hematopoietic Stem‐Cell Rescue for Multiply Relapsed/Refractory Pediatric Germ Cell Tumors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Although most malignant germ cell tumors (GCTs) are highly curable with cisplatin‐based therapy, options for patients with multiply relapsed/refractory disease remain limited. For this population, we report the first pediatric use of gemcitabine, docetaxel, melphalan, and carboplatin (GemDMC) as part of sequential cycles of high‐dose ...
Maria Frost   +10 more
wiley   +1 more source

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