Results 71 to 80 of about 19,607,477 (309)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

What if online students take on the responsibility: Students’ cognitive presence and peer facilitation techniques

open access: yesOnline Learning, 2019
The purpose of this study was to investigate: (a) the characteristics of online students’ cognitive presence in a peer-facilitated discussion environment, and (b) the peer facilitation techniques that enhance cognitive presence development.
Ye Chen, Jing Lei, Jiaming Cheng
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Service Experience at Passport Seva Kendra

open access: yesVikalpa, 2021
Richa Saxena, Sapna Popli, Abhishek
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Interpreting Research: The Art and Science of an Effective Discussion [PDF]

open access: yesClinovate: Advances in Medicine and Healthcare
The Discussion section of a research paper plays a crucial role in analyzing findings, comparing them with existing literature, and identifying their broader significance. This article explores the key elements of an effective Discussion, differentiating
Saumitraa Awasthi   +2 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Multivalvular Heart Disease: A Bedside Case Discussion for Residents

open access: yesJournal of the Practice of Cardiovascular Sciences
A middle-aged patient presented with symptoms of shortness of breath. He had been operated for a heart disease many years ago. He had a history of cough, hemoptysis, and a recent febrile episode. Clinical examination revealed a slow rising pulse and both
Prerna Garg, Saurav Suman, Abhinav Jain
doaj   +1 more source

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