Results 101 to 110 of about 4,880,932 (242)
Argumentation in socio-scientific discussions [PDF]
Investigações em Ensino de Ciências, 2013 This study aimed to understand the development of the argument in socio-scientific discussions in Chemistry lessons. Were investigated classes of three teachers in public schools in high school of the Federal District – Brazil to identify the occurrence ...
Mírian Rejane Magalhães Mendes +1 more
doaj
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Elluminate Article: Content Analysis of Online Asynchronous Discussions
International Review of Research in Open and Distributed Learning, 2005 The publisher of IRRODL, The Canadian Institute of Distance Education Research (CIDER), is pleased to link here to a series of eight online seminars that took place over Spring 2005, using Elluminate live e-learning and collaborative solutions.
Elizabeth Murphy
doaj
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Concepts, Strategies and Proposals for the development of Urban Communities
Lahore Journal of EconomicsA recent discussion conducted by the Anjuman Mimaran1 has generated a concept for urban development that has immediate relevance to Pakistan. It is based on high-density, low-rise, low-tech development that integrates housing employment and social ...
The Anjuman Mimaran Urban Project
doaj