Results 61 to 70 of about 7,871 (139)

Historias del diseño

open access: yesAnales del Instituto de Arte Americano e Investigaciones Estéticas "Mario J. Buschiazzo", 2013
El presente texto se inicia con una revisión de algunos de los enfoques que se han dado a la historia del diseño para ofrecer un marco ubicado dentro del contexto global.
Luis Rodríguez Morales
doaj  

Non-Nucleoside Lycorine-Based Analogs as Potential DENV/ZIKV NS5 Dual Inhibitors: Structure-Based Virtual Screening and Chemoinformatic Analysis

open access: yesMetabolites
Dengue (DENV) and Zika (ZIKV) virus continue to pose significant challenges globally due to their widespread prevalence and severe health implications. Given the absence of effective vaccines and specific therapeutics, targeting the highly conserved NS5 ...
Adrián Camilo Rodríguez-Ararat   +7 more
doaj   +1 more source

Obtaining biocompatible ceramic scaffolds of calcium phosphates through ceramic stereolithography

open access: yesJournal of Materials Science: Materials in Medicine
Ceramic stereolithography scaffolds with designs based on triple periodic minimal surfaces (TPMS) were developed for potential applications in bone tissue regeneration. An acrylic-based resin with calcium phosphate nanoparticles were used. Particles were
Carolina Duque-Uribe   +8 more
doaj   +1 more source

Development of a Sustainable Thermoplastic Composite Material Using Manicaria saccifera Fabric and Elium® Resin

open access: yesJournal of Natural Fibers
The massive production of nonrenewable materials has exacerbated global environmental challenges, necessitating the development of sustainable alternatives.
Juan Porras   +5 more
doaj   +1 more source

Saccharomyces cerevisiae biofactory to produce naringenin using a systems biology approach and a bicistronic vector expression strategy in flavonoid production

open access: yesMicrobiology Spectrum
Naringenin is the central flavonoid in the biosynthesis of several bioactive compounds and presents a growing demand for its nutraceutical properties.
Luis Alberto Mejía-Manzano   +7 more
doaj   +1 more source

dyphAI dynamic pharmacophore modeling with AI: a tool for efficient screening of new acetylcholinesterase inhibitors

open access: yesFrontiers in Chemistry
Therapeutic strategies for Alzheimer’s disease (AD) often involve inhibiting acetylcholinesterase (AChE), underscoring the need for novel inhibitors with high selectivity and minimal side effects.
Yasser Hayek-Orduz   +10 more
doaj   +1 more source

FlavorMiner: a machine learning platform for extracting molecular flavor profiles from structural data

open access: yesJournal of Cheminformatics
Flavor is the main factor driving consumers acceptance of food products. However, tracking the biochemistry of flavor is a formidable challenge due to the complexity of food composition. Current methodologies for linking individual molecules to flavor in
Fabio Herrera-Rocha   +7 more
doaj   +1 more source

INCERTIDUMBRE EN LA INTEGRACIÓN DE PROCESOS PARA EL DESARROLLO DE BIOREFINERÍAS

open access: yesRevista Centro Azúcar, 2015
En el trabajo se muestra cómo los enfoques de diseño con grado óptimo de flexibilidad  pueden reducir los costos adicionales de las estrategias que aplican factores de  sobrediseño para considerar parámetros con incertidumbre que influyen en la ...
Meilyn González Cortés   +3 more
doaj  

[Management by objectives and funding of primary care teams: Critical reflections]. [PDF]

open access: yesAten Primaria
Bayona-Huguet X   +2 more
europepmc   +1 more source

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