Results 191 to 200 of about 10,142,751 (308)

Vaginal cancer in the second trimester of pregnancy: Successful conservative surgery and 21-year disease-free survival. [PDF]

Gynecol Oncol Rep
Tjalma W, Caris Alias Reynders F, Eelen C, Konje J, Deckers F, Joye I, Papadimitriou K, Subbian A.   +7 more
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Prognostic value of ultrasound Breast Imaging Reporting and Data System for disease-free survival in early-stage breast cancer: a retrospective study (2011-2018). [PDF]

Quant Imaging Med Surg
You Z, Hou R, Zhang R, Zhang M, Wu Y, Zhang K, Li J.   +6 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Association of Metastatic Lymph Node Count and Primary Tumor Size with Disease-Free Survival in Stage II-III Gastric Cancer: A Retrospective Cohort Study. [PDF]

Medicina (Kaunas)
Kanatsız E, Sezgin Y, Yılmaz Ürün Y.
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Eight-year disease-free survival in clear cell adenocarcinoma of the urethra with surgery alone: a case report and literature review. [PDF]

Front Oncol
Wang J, Sun Y, Jiang B, Hou S, Liu Z.
europepmc   +1 more source

Analysis of survival and disease free survival of four hundred and fifty-two lobular carcinomas

, 2003
Baltas, D, Vourli, G, Chrisanthakis, D, Keramopoullous, A, Bredakis, N, Pavlaki, K, Louis, J, Gaki, V   +7 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Preoperative nutritional status and sarcopenia are associated with disease-free survival in patients with resected pancreatic neuroendocrine tumors. [PDF]

Front Oncol
Li J, Lai M.
europepmc   +1 more source