Results 121 to 130 of about 26,337,030 (428)
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
Current Gastroenterology Reports, 2001 Abstract Whipple’s disease is an uncommon infection caused by the actinomycete Tropheryma whipplei, most commonly diagnosed when overt small intestinal disease leads to malabsorption, but with protean other clinical manifestations (e.g. systemic, neurological, or cardiological).
Florence Fenollar, Didier Raoult
openaire +5 more sources
Time series analysis of Parkinson's disease, Huntington's disease and Amyotrophic Lateral Sclerosis [PDF]
arXiv, 2013 The aim of this paper is to study the (clinical) time-series data of three diseases with complex dynamics: Parkinson's disease, Huntington's disease and Amyotrophic Lateral Sclerosis. For this purpose, first all of the time series data are embedded in a vector space of suitable dimension and then the correlation dimension of the above mentioned ...
arxiv
Analysis of the human diseasome reveals phenotype modules across common, genetic, and infectious diseases [PDF]
, 2014 Phenotypes are the observable characteristics of an organism arising from its response to the environment. Phenotypes associated with engineered and natural genetic variation are widely recorded using phenotype ontologies in model organisms, as are signs and symptoms of human Mendelian diseases in databases such as OMIM and Orphanet.
arxiv +1 more source
Environmental toxicity influences disease spread in consumer population [PDF]
arXiv, 2022 The study of infectious disease has been of interest to ecologists since long. The initiation of epidemic and the long term disease dynamics are largely influenced by the nature of the underlying consumer (host)-resource dynamics. Ecological traits of such systems may be often modulated by toxins released in the environment due to ongoing anthropogenic
arxiv
500 Cities Project: Local Data for Better Health 2014 [PDF]
, 2016 The 500 Cities Project-Local Data for Better Health-is a collaboration among the Robert Wood Johnson Foundation, the CDC Foundation, and the Centers for Disease Control and Prevention (CDC), whose purpose is to provide high quality small area estimates ...
Center for Disease Control and Prevention +1 more
core +1 more source
, 2010 Unani (also spelt Yunani) refers to the tradition of Graeco-Arabic medicine. Like Ayurveda, this also a comprehensive tradition of medicine that goes back of Hippocrates, but owes a lot to the wisdom and experience of Arabic and Persian physicians. India
Joshi, Himanshu +3 more
core +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source